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A Trial of Intravenous Denileukin Diftitox in Stage III or IV Ovarian Cancer Summary This study tests whether denileukin diftitox will deplete regulatory T cells, boost tumor-specific immunity and treat epithelial ovarian cancer in patients who have failed, or who are ineligible for front line therapy.
View Full Description Full Description This is a non-randomized, single-arm, Phase II trial. Selected patients with advanced-stage epithelial ovarian cancers who have no reasonable chance of cure using standard regimens, or who will not receive such regimens (due to contraindication or intolerance) are eligible. Patients will be treated with Ontak at 12 µg/kg monthly as long as they meet response criteria.
View Eligibility Criteria Eligibility Criteria Inclusion Criteria:
Check Your Eligibility
Let’s see if you might be eligible for this study.
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There is 1 Location for this study
CTRC at UTHSCSA
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