Ovarian Cancer Clinical Trial

e-Health Intervention (Day-by-Day) for the Management of Fear of Progression in Women With Stage III or IV Gynecologic Cancer: A Pilot Study

Summary

This clinical trial studies how well an electronic (e)-health intervention (day-by-day) woks in managing fears or worries about cancer growing, spreading, or getting worse (progression) in patients with stage III or IV gynecologic cancer. Fear and worries about cancer progression or recurrence (coming back) are common concerns. This may contribute to concerns related to illness, worries, and uncertainty about the future. Day by Day is adapted from a program called "Conquer Fear" which was shown to benefit patients with early-stage cancer. Day-by-day intervention may help refocus patient thoughts and help patients learn skills to manage anxiety and fears.

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Full Description

PRIMARY OBJECTIVES:

I. Will adapt the intervention into a hybrid format including two group and three web based self-study sessions. (Phase 1) II. To determine the feasibility and acceptability of a new hybrid e-health intervention to manage fear of progression (FOP) in patients with stage III or IV gynecologic (GYN) cancer. (Phase 2)

SECONDARY OBJECTIVE:

I. To explore the preliminary efficacy of day-by-day (DBD) on reducing FOP (primary outcome) and improving secondary outcomes of distress, anxiety, depression, metacognitions, and mindfulness. (Exploratory)

OUTLINE:

PHASE I (DEVELOPMENT): Patients complete surveys and participate in focus groups.

PHASE II (DBD): Patients receive DBD intervention consisting of group and web-based self-study sessions and check-in calls on study. Patients also watch videos and receive handouts to reinforce the group sessions.

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Eligibility Criteria

Inclusion Criteria:

Women with stage III or IV GYN cancer (ovarian, endometrial, cervical, vulvar/vaginal);at least 3 months from initial diagnosis
Age: >= 18 years
Score >= 34 on the Fear of Progression Short-Form, indicating dysfunctional levels
Ability to read and understand English
Patients in remission or with progressive disease are eligible

Exclusion Criteria:

Enrolled in hospice
Severe depression as assessed by Patient Health Questionnaire (PHQ-9)
Non-English speaking
Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)

Study is for people with:

Ovarian Cancer

Estimated Enrollment:

75

Study ID:

NCT05786456

Recruitment Status:

Not yet recruiting

Sponsor:

City of Hope Medical Center

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There is 1 Location for this study

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City of Hope Medical Center
Duarte California, 91010, United States More Info
Anne Reb
Contact
626-218-2987
Anne Reb
Principal Investigator

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Study is for people with:

Ovarian Cancer

Estimated Enrollment:

75

Study ID:

NCT05786456

Recruitment Status:

Not yet recruiting

Sponsor:


City of Hope Medical Center

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