Prostate Cancer Clinical Trial
A Study of Galeterone Compared to Enzalutamide In Men Expressing Androgen Receptor Splice Variant-7 mRNA (AR-V7) Metastatic CRPC
Summary
The purpose of this study is to compare galeterone to enzalutamide in men expressing androgen receptor spice variant-7 mRNA (AR-V7) in metastatic (M1) castrate resistant prostate cancer (CRPC).
View Eligibility Criteria
Eligibility Criteria
Inclusion Criteria:
Progressive metastatic (M1) disease on androgen deprivation therapy
Detectable AR-V7 from circulating tumors (CTCs)
ECOG performance status 0 or 1
Exclusion Criteria:
Prior treatment with second generation anti-androgens (e.g. abiraterone, enzalutamide)
Prior treatment with chemotherapy for CRPC
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There are 113 Locations for this study
See Locations Near You
Pinnacle Oncology Hematology
Scottsdale Arizona, 85258, United States
Scottsdale Arizona, 85258, United States
University Of Arizona Cancer Center
Tucson Arizona, 85724, United States
Tucson Arizona, 85724, United States
City of Hope
Duarte California, 91010, United States
Duarte California, 91010, United States
USC Norris Comprehensive Cancer Center
Los Angeles California, 90033, United States
Los Angeles California, 90033, United States
UCLA Jonsson Comprehensive Cancer Center
Los Angeles California, 90095, United States
Los Angeles California, 90095, United States
Prostate Oncology Specialists, Inc.
Marina Del Rey California, 90292, United States
Marina Del Rey California, 90292, United States
UC Davis Cancer Center
Sacramento California, 95817, United States
Sacramento California, 95817, United States
San Bernardino Urological Associates
San Bernardino California, 92404, United States
San Bernardino California, 92404, United States
Urology Speciality Group
Torrance California, 90505, United States
Torrance California, 90505, United States
University of Colorado Cancer Center Anschultz Cancer Pavilion
Aurora Colorado, 80045, United States
Aurora Colorado, 80045, United States
The Urology Center of Colorado
Denver Colorado, 80211, United States
Denver Colorado, 80211, United States
Yale University School of Medicine
New Haven Connecticut, 06510, United States
New Haven Connecticut, 06510, United States
Georgetown University Medical Center
Washington District of Columbia, 20007, United States
Washington District of Columbia, 20007, United States
Sibley Memorial Hospital
Washington District of Columbia, 20016, United States
Washington District of Columbia, 20016, United States
Boca Raton Community Hospital, Inc.
Boca Raton Florida, 33486, United States
Boca Raton Florida, 33486, United States
University of Florida Health Cancer Center
Orlando Florida, 32806, United States
Orlando Florida, 32806, United States
Moffitt Cancer Center
Tampa Florida, 33612, United States
Tampa Florida, 33612, United States
First Urology
Jeffersonville Indiana, 47130, United States
Jeffersonville Indiana, 47130, United States
Tulane Medical Center
New Orleans Louisiana, 70115, United States
New Orleans Louisiana, 70115, United States
Regional Urology, LLC
Shreveport Louisiana, 71106, United States
Shreveport Louisiana, 71106, United States
University of Maryland Greenenbaum Cancer Center
Baltimore Maryland, 21201, United States
Baltimore Maryland, 21201, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore Maryland, 21205, United States
Baltimore Maryland, 21205, United States
Walter Reed National Military Medical Center
Bethesda Maryland, 20307, United States
Bethesda Maryland, 20307, United States
Massachusetts General Hospital
Boston Massachusetts, 02114, United States
Boston Massachusetts, 02114, United States
Dana-Farber Cancer Institute
Boston Massachusetts, 02115, United States
Boston Massachusetts, 02115, United States
Beth Israel Deaconess Medical Center
Boston Massachusetts, 02215, United States
Boston Massachusetts, 02215, United States
University of Michigan Health System
Ann Arbor Michigan, 48109, United States
Ann Arbor Michigan, 48109, United States
Karmanos Cancer Center
Detroit Michigan, 48201, United States
Detroit Michigan, 48201, United States
Urology Cancer Center and GU Research Network
Omaha Nebraska, 68130, United States
Omaha Nebraska, 68130, United States
Coastal Urology Associates
Brick New Jersey, 08724, United States
Brick New Jersey, 08724, United States
Brooklyn Urology Research Group
Brooklyn New York, 11215, United States
Brooklyn New York, 11215, United States
Advanced Urology Centers of New York
Plainview New York, 11803, United States
Plainview New York, 11803, United States
Premier Medical Group of the Hudson Valley
Poughkeepsie New York, 12601, United States
Poughkeepsie New York, 12601, United States
Associated Medical Professionals of NY
Syracuse New York, 13210, United States
Syracuse New York, 13210, United States
University of North Carolina Lineberger Cancer Center
Chapel Hill North Carolina, 27599, United States
Chapel Hill North Carolina, 27599, United States
Carolina Urology Partners, PLLC
Charlotte North Carolina, 28277, United States
Charlotte North Carolina, 28277, United States
Carolina Urology Partners
Concord North Carolina, 28025, United States
Concord North Carolina, 28025, United States
The Urology Group
Cincinnati Ohio, 45212, United States
Cincinnati Ohio, 45212, United States
Clinical Research Solutions
Middleburg Heights Ohio, 44130, United States
Middleburg Heights Ohio, 44130, United States
Oregon Urology Institute
Springfield Oregon, 97477, United States
Springfield Oregon, 97477, United States
Lancaster Urology
Lancaster Pennsylvania, 17604, United States
Lancaster Pennsylvania, 17604, United States
Fox Chase Cancer Center
Philadelphia Pennsylvania, 19111, United States
Philadelphia Pennsylvania, 19111, United States
UPMC Cancer Centers
Pittsburgh Pennsylvania, 15232, United States
Pittsburgh Pennsylvania, 15232, United States
Carolina Urologic Research Center
Myrtle Beach South Carolina, 29572, United States
Myrtle Beach South Carolina, 29572, United States
Urology Associates Clinical Research
Nashville Tennessee, 37209, United States
Nashville Tennessee, 37209, United States
Urology Clinics of North Texas
Dallas Texas, 75231, United States
Dallas Texas, 75231, United States
Texas Oncology/Baylor University Medical Center
Dallas Texas, 75246, United States
Dallas Texas, 75246, United States
Urology San Antonio
San Antonio Texas, 78229, United States
San Antonio Texas, 78229, United States
Virginia Urology
Richmond Virginia, 23235, United States
Richmond Virginia, 23235, United States
Urology of Virginia
Virginia Beach Virginia, 23462, United States
Virginia Beach Virginia, 23462, United States
The University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
Madison Wisconsin, 53792, United States
Madison Wisconsin, 53792, United States
St. George Private Hospital, Oncology Day Care Centre
Kogarah New South Wales, 2217, Australia
Kogarah New South Wales, 2217, Australia
Ashford Cancer Centre/Adelaide Cancer Centre Research
Kurralta Park New South Wales, 5037, Australia
Kurralta Park New South Wales, 5037, Australia
North Coast Cancer Institute
Port Macquarie New South Wales, 2444, Australia
Port Macquarie New South Wales, 2444, Australia
Prince of Wales Hospital
Randwick New South Wales, 2031, Australia
Randwick New South Wales, 2031, Australia
Macquarie University
Sydney New South Wales, 2109, Australia
Sydney New South Wales, 2109, Australia
Peninsula Specialist Centre
Kippa-Ring Queensland, 4102, Australia
Kippa-Ring Queensland, 4102, Australia
ICON Cancer Care
Southport Queensland, 4215, Australia
Southport Queensland, 4215, Australia
Princess Alexandra Hospital
Woolloongabba Queensland, 4102, Australia
Woolloongabba Queensland, 4102, Australia
Ashford Cancer Centre/Adelaide Cancer Centre Research
Kurralta Park South Australia, 5037, Australia
Kurralta Park South Australia, 5037, Australia
Box Hill Hospital
Box Hill Victoria, 3128, Australia
Box Hill Victoria, 3128, Australia
Monash Medical Centre
East Bentleigh Victoria, 3165, Australia
East Bentleigh Victoria, 3165, Australia
Peter MacCallum Cancer Centre
East Melbourne Victoria, 3002, Australia
East Melbourne Victoria, 3002, Australia
Cabrini Hospital
Malvern Victoria, 3144, Australia
Malvern Victoria, 3144, Australia
Jules Bordet Institute Clinique d'Oncologie Medicale
Brussels , B-100, Belgium
Brussels , B-100, Belgium
Universitair Ziekenhuis Gent
Gent , B-900, Belgium
Gent , B-900, Belgium
Jessa Ziekenhuis
Hasselt , B-350, Belgium
Hasselt , B-350, Belgium
CHU Sart Tilman
Liège , 4000, Belgium
Liège , 4000, Belgium
British Columbia Cancer
Kelowna British Columbia, V1Y 5, Canada
Kelowna British Columbia, V1Y 5, Canada
British Columbia Cancer
Vancouver British Columbia, V5Z 4, Canada
Vancouver British Columbia, V5Z 4, Canada
London Health Sciences Centre
London Ontario, N6A 4, Canada
London Ontario, N6A 4, Canada
Sunnybrook Research Institute
Toronto Ontario, M4N 3, Canada
Toronto Ontario, M4N 3, Canada
Princess Margaret Hospital
Toronto Ontario, M5G 2, Canada
Toronto Ontario, M5G 2, Canada
Centre Hospitalier De I'Universite de Montreal
Montreal Quebec, H2L 4, Canada
Montreal Quebec, H2L 4, Canada
Centre Hospitalier Universitaire de Quebec
Quebec City Quebec, G1R 3, Canada
Quebec City Quebec, G1R 3, Canada
Centre Paul Papin
Angers Cedex 9 , 49055, France
Angers Cedex 9 , 49055, France
Institut Sainte Catherine
Avignon , 84918, France
Avignon , 84918, France
Institut Bergonié
Bordeaux , 33076, France
Bordeaux , 33076, France
Centre François Baclesse
Caen Cedex , 14076, France
Caen Cedex , 14076, France
Service de Médecine Interne Onco-Hématologie
La Roche Sur Yon Cedex 9 , 85925, France
La Roche Sur Yon Cedex 9 , 85925, France
Clinique Victor Hugo Centre Jean Bernard
Le Mans , 72000, France
Le Mans , 72000, France
Centre Léon Bérard
Lyon , 69008, France
Lyon , 69008, France
Hôpital Edouard Herriot
Lyon , Cedex, France
Lyon , Cedex, France
Centre Antoine Lacassagne
Nice Cedex 2 , 06189, France
Nice Cedex 2 , 06189, France
Institut de Cancérologie de l'Ouest
Saint Herblain , 44805, France
Saint Herblain , 44805, France
Institut de Cancerlogie de la Loire
Saint Priest en Jarez , 42271, France
Saint Priest en Jarez , 42271, France
Centre René Gauducheau
Saint-Herblain , 44805, France
Saint-Herblain , 44805, France
Institut Gustave-Roussy
Villejuif , 94805, France
Villejuif , 94805, France
Centro Oncologico c/o Presidio Ospedaliero San Donato - Arezzo
Arezzo , 52100, Italy
Arezzo , 52100, Italy
Unità Operativa di Oncologia Ospedale Civile degli Infe
Faenza (RA) , 48018, Italy
Faenza (RA) , 48018, Italy
Romagnolo per lo Studio e la Cura dei Tumori IRST-IRCCS - Oncologia medica
Meldola (FC) , 47014, Italy
Meldola (FC) , 47014, Italy
AOU "S. Luigi", SCDU Oncologia Medica
Orbassano (Torino) , 10043, Italy
Orbassano (Torino) , 10043, Italy
Az. Ospedaliera San Camillo-Forlanini
Roma , 00152, Italy
Roma , 00152, Italy
University of Turin
Torino , 10126, Italy
Torino , 10126, Italy
Santa Chiara Hospital
Trento , 38122, Italy
Trento , 38122, Italy
Hospital ClÃnic i Provincial de Barcelona-Oncology
Barcelona , 08036, Spain
Barcelona , 08036, Spain
Instituto Catalan de Oncologia (Hospital Durans i Reynals)
Barcelona , 08908, Spain
Barcelona , 08908, Spain
Hospital General Universitario de Elche
Elche , 3203, Spain
Elche , 3203, Spain
Hospital General Universitario Gregorio Marañón
Madrid , 28009, Spain
Madrid , 28009, Spain
Spanish National Cancer Research Centre
Madrid , 28050, Spain
Madrid , 28050, Spain
Unidad Cnio Ibima de Investigacion en Prostata
Malaga , , Spain
Malaga , , Spain
Fundación Althaia Manresa
Manresa , 08243, Spain
Manresa , 08243, Spain
Hospital Son Espases - OncologÃa
Palma de Mallorca , 07010, Spain
Palma de Mallorca , 07010, Spain
Hospital Clinico Universitario de Navarra
Pamplona , 31008, Spain
Pamplona , 31008, Spain
Consorci Hospitalari de Parc TaulÃ
Sabadell , 08208, Spain
Sabadell , 08208, Spain
Hospital Universitario Virgen del Rocio
Sevilla , 41013, Spain
Sevilla , 41013, Spain
IVO-OncologÃa Médica
Valencia , 46009, Spain
Valencia , 46009, Spain
CR-UK Institute for Cancer Studies
Birmingham England, B15 2, United Kingdom
Birmingham England, B15 2, United Kingdom
Sussex Cancer Centre
Brighton England, BN2 5, United Kingdom
Brighton England, BN2 5, United Kingdom
University College of London Hospitals
London England, NWI 2, United Kingdom
London England, NWI 2, United Kingdom
Guy's and St. Thomas' NHS Foundation Trust
London England, SE1 9, United Kingdom
London England, SE1 9, United Kingdom
Southampton General Hospital
Southampton England, SO16 , United Kingdom
Southampton England, SO16 , United Kingdom
University of Surrey Post Graduate Medical Hospital
Surrey England, GU2 7, United Kingdom
Surrey England, GU2 7, United Kingdom
Royal Marsden Hospital
Surrey England, SM2 5, United Kingdom
Surrey England, SM2 5, United Kingdom
The Royal Cornwall Hospital
Truro England, TR1 3, United Kingdom
Truro England, TR1 3, United Kingdom
The Beatson West of Scotland Cancer Centre
Glasgow Scotland, G12 0, United Kingdom
Glasgow Scotland, G12 0, United Kingdom
Velindre Hospital
Cardiff Wales, CF14 , United Kingdom
Cardiff Wales, CF14 , United Kingdom
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