Prostate Cancer Clinical Trial
Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer
Summary
This study is being done to determine whether levels of prostate cancer derived extracellular vesicles from blood and urine specimens correlate with response to primary local treatment (surgery) in prostate cancer.
Full Description
PRIMARY OBJECTIVES:
I. Determine the levels of prostate cancer-derived extracellular vesicles pre- and post-radical prostatectomy.
II. Determine the correlation between levels of prostate cancer-derived extracellular vesicles and PSA.
OUTLINE: This is an observational study. Participants are assigned to 1 of 2 cohorts.
COHORT I: Prostate cancer patients undergo blood and urine sample collection on study. Patients' medical records are also reviewed.
COHORT II: Female urology clinic patients and female volunteers undergo blood and urine sample collection on study.
Eligibility Criteria
Inclusion Criteria:
* PROSTATE CANCER PATIENTS:
Age 18+
Able to give informed consent
Patients with prostate cancer
Patients treated with primary prostatectomy
The focus will be on high-risk patients with at least one of either criterion:
PSA >= 20 ng/ml
AND/OR Gleason >= 8
AND/OR clinical stage >= T3
* FEMALE CONTROL PATIENTS:
Age 18+
Able to give informed consent
Exclusion Criteria:
* PROSTATE CANCER PATIENTS:
Unable or unwilling to provide informed consent
Metastatic prostate cancer - defined evidence of metastatic disease on pre-procedural testing
* FEMALE CONTROL PATIENTS:
Unable or unwilling to provide informed consent
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There is 1 Location for this study
Rochester Minnesota, 55905, United States More Info
Principal Investigator
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