Prostate Cancer Clinical Trial

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Docetaxel in Combination With GVAX ® Immunotherapy Versus Docetaxel and Prednisone in Prostate Cancer Patients

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Summary

The primary objective of this study is to compare the duration of survival between patients receiving docetaxel in combination with the GVAX® vaccine for prostate cancer versus patients receiving docetaxel and prednisone treatment in patients with prostate cancer who no longer respond to hormone therapy, who have documented metastases with pain. Patients may have had up to one prior non-taxane chemotherapy treatment.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Confirmed diagnosis of or clinical history consistent with adenocarcinoma of the prostate
Metastatic prostate cancer deemed to be unresponsive or refractory to hormone therapy
Detectable metastases
ECOG performance status ≤2 (Performance status of 3 if due to bone pain)
Any Gleason score
Only one prior treatment with systemic chemotherapy
No prior treatment with gene therapy
No prior immunotherapy for prostate cancer
Taxane naïve
Experiencing cancer-related pain

Study is for people with:

Prostate Cancer

Phase:

Phase 3

Estimated Enrollment:

408

Study ID:

NCT00133224

Recruitment Status:

Terminated

Sponsor:

Cell Genesys

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There are 114 Locations for this study

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Alaska Clinical Research Center
Anchorage Alaska, 99508, United States
St. Edward Mercy Medical Center
Fort Smith Arkansas, 72917, United States
Loma Linda University
Loma Linda California, 92354, United States
Onocology Care Medical Associates
Los Angeles California, 90057, United States
Desert Hematology Oncology Medical Group
Rancho Mirage California, 92270, United States
San Bernardino Urology Associates
San Bernardino California, 92404, United States
Kaiser Permanente Medical Group Dept. of Oncology Research
San Diego California, 92120, United States
Sharp Healthcare
San Diego California, 92123, United States
California Pacific Medical Center
San Francisco California, 94115, United States
UCSF Mt. Zion Cancer Center
San Francisco California, 94115, United States
Cancer Research & Prevention Center
Soquel California, 95073, United States
Cancer Center and Department of Medicine
Aurora Colorado, 80010, United States
Mayo Clinic - Jacksonville
Jacksonville Florida, 32224, United States
Jupiter Hematology & Oncology Associates
Jupiter Florida, 33458, United States
Lakeland Regional Cancer Center
Lakeland Florida, 33804, United States
Hematology Oncology Associates of the Treasure Coast
Port St. Lucie Florida, 34952, United States
Atlanta VA Medical Center
Atlanta Georgia, 30033, United States
Peachtree Hematology & Oncology Consultants, PC
Atlanta Georgia, 30309, United States
Emory Winship Cancer Institute
Atlanta Georgia, 30322, United States
Medical & Surgical Specialists
Galesburg Illinois, 61401, United States
James Graham Brown Cancer Center
Louisville Kentucky, 40202, United States
Frederick Memorial Hospital Regional Cancer Therapy Center
Frederick Maryland, 21701, United States
General Clinical Research Center University of Michigan
Ann Arbor Michigan, 48109, United States
Billings Clinic
Billings Montana, 59101, United States
Hematology & Oncology Consultants P.C.
Omaha Nebraska, 68122, United States
Nevada Cancer Institute
Las Vegas Nevada, 89135, United States
Hackensack University Medical Center
Hackensack New Jersey, 07601, United States
New Mexico Oncology
Albuquerque New Mexico, 87109, United States
North Shore Hematology Oncology Associates P.C.
East Setauket New York, 11733, United States
NYU Clinical Cancer Center
New York New York, 10016, United States
Presbyterian Hospital Center for Cancer Research
Charlotte North Carolina, 28204, United States
Gabrail Cancer Center
Canton Ohio, 44718, United States
Providence Portland Medical Center
Portland Oregon, 97213, United States
Kaiser Permanente Oncology/Hematology
Portland Oregon, 97227, United States
Cancer Centers of the Carolinas
Greenville South Carolina, 29605, United States
The West Clinic
Memphis Tennessee, 38120, United States
Center for Oncology Research & Treatment, PA
Dallas Texas, 75230, United States
Dallas Oncology Consultants
Dallas Texas, 75237, United States
Mary Crowley Medical Research Center
Dallas Texas, 75246, United States
Mobley Research Center
Houston Texas, 77024, United States
Northwest Cancer Center
Houston Texas, 77042, United States
Urology San Antonio Research, PA
San Antonio Texas, 78229, United States
Seattle Cancer Care Alliance, Univ. of Washington
Seattle Washington, 98109, United States
Ziekenhuis Netwerk Antwerpen - AZ Middelheim
Antwerpen , B-202, Belgium
V.Z.W. Imelda Ziekenhuis
Bonheiden , B-282, Belgium
AZ Groeninge
Kortrijk , B-850, Belgium
CHU de Liège - Hôpital du Sart Tilman
Liège , B-400, Belgium
Heilig-Hartziekenhuis Campus Wilgenstraat
Roeselare , B- 88, Belgium
Regionaal Ziekenhuis Sint Trudo
Sint Truiden , B-380, Belgium
Centre Hospitalier de L'Universite de Montreal
Montreal Quebec, H2L 4, Canada
Centre Hospitalier Universite de Sherbrooke
Sherbrooke Quebec, J1H 5, Canada
Centre Regional de lutte contre le cancer Paul Papin
Angers , 49033, France
Centre Francois Baclesse
Caen , 14076, France
Institut Jean Godinot, Oncologie Medicale
Cedex , 51056, France
Centre Jean Perrin Centre Régional de lutte contre le cancer d'Auvergne
Clermont-Ferrand , 63011, France
Centre Rene Gauducheau - Site Hospitalier Nord
Nantes , 44805, France
Centre Antoine Lacassagne - Centre Regional de lutte contre le cancer
Nice , 06189, France
CHU Saint Louis
Paris , 75010, France
Hopital Saint Joseph Site Saint Michel
Paris , 75015, France
Hopital Cochin
Paris , 75674, France
CHU Poitiers
Poitiers , 86021, France
Centre Hospitalier Rene Dubos
Pontoise , 95303, France
Clinique Armoricaine de Radiology
Saint Brieuc , 22015, France
Hopital Civil
Strasbourg , 67091, France
CHU Bretonneau
Tours , 37044, France
Centre Alexis Vautrin
Vandoeuvre les Nancy , 54500, France
Universitatsklinikum Aachen
Aachen , 52074, Germany
Charite Campus Mitte
Berlin , 10117, Germany
Krankenhaus Am Urban
Berlin , 10967, Germany
Universitatsklinikum Carl Gustav Carus An Der
Dresden , 01307, Germany
Klinikum der Johann Wolfgang Goethe-Universitat
Frankfurt am Main , 60590, Germany
Urologische Klinik und Poliklinik der Johannes Gutenberg Universitat Mainz
Mainz , 55131, Germany
Klinikum Mannheim
Mannheim , 68135, Germany
Urologische Klinik und Poliklinik
Munchen , 81675, Germany
Istituto Nazionale dei Tumori
Milano , 20133, Italy
Fondazione IRCCS Ospedale Maggiore Policlinico
Milan , 20122, Italy
Fondazione San Raffaele del Monte Tabor
Milan , 20132, Italy
Istituto Europeo di Oncologia
Milan , 20141, Italy
Azienda Ospedaliero Universitaria di Modena
Modena , 41100, Italy
Azienda Ospedaliera Maggiore della Carita
Novarra , 28100, Italy
Azienda Ospedaliera di Parma
Parma , 43100, Italy
Azienda Ospedaliero Universitaria (A.O.U.) Pisana-Ospedale S. Chiara
Pisa , 56126, Italy
Azienda Ospedaliera San Camillo Forlanini
Roma , 00152, Italy
Presidio Ospedaliero di Sassari-Ospedale SS. Anunziata
Sassari , 07100, Italy
A.S.O. San Giovanni Battista di Torino
Turin , 10126, Italy
VU Medisch Centrum
Amsterdam , 1081 , Netherlands
Academisch Centrum
Amsterdam , 1105 , Netherlands
Universitair Medisch Centrum Groningen
Groningen , 9713 , Netherlands
Samodzielny Publiczny Zaklad Opieki Zdrowotnej
Bialystok , 15-95, Poland
Samodzielny Publiczny Zaklad Opieki Zdrowotnej
Bytom , 41-90, Poland
Katedra i Klinika Onkologii i Radioterapli
Gdansk , 80-95, Poland
Samodzielny Publiczny Zaklad Opieki Zdrowotnej
Katowice , 40-07, Poland
Centrum Onkologii Instytut im. Marii Sklodowskiej-Curie Oddzial w Krakowie
Krakow , 31-11, Poland
Wojewodzki Szpital Specjalistyczny im. M. Kopernika
Lodz , 93-50, Poland
Samodzielny Publiczny Szpital Kliniczny nr 1 Przemienienia Panskiego AM w Poznaniu
Poznan , 61-84, Poland
Wojewodzki Szpital Specjalistyczny w Siedlcach
Siedlce , 08-11, Poland
Wojewodzki Szpital Specjalistyczny Oddzial Urologii
Slupsk , 76-20, Poland
Szpital Kliniczny Dzieciatka Jezus - Centrum Leczenia Obrazen
Warszawa , 02-00, Poland
Centrum Onkologii Instytut im. Marii Sklodowskiej- Curie
Warszawa , 02-78, Poland
Universitetssjukhuset i Lund
Lund , SE-22, Sweden
University Hospital MAS (UMAS)
Malmo , SE-20, Sweden
Akademiska Sjukhuset i Uppsala
Uppsala , SE-75, Sweden
Addenbrookes Hospital
Cambridge , CB2 2, United Kingdom
Royal Surrey County Hospital
Guildford , GU2 7, United Kingdom
St. James University Hospital
Leeds , LS9 7, United Kingdom
Lincoln County Hospital
Lincoln , LN2 4, United Kingdom
Royal Marsden Hospital
London , SW3 6, United Kingdom
Department of Oncology Hammersmith Hospital
London , W12 0, United Kingdom
Christie Hospital Manchester
Manchester , M20 4, United Kingdom
Mount Vernon Hospital
Middlesex , HA6 2, United Kingdom
Nottingham City Hospital
Nottingham , NG5 1, United Kingdom
Rosemere Cancer Centre, Royal Preston Hospital
Preston , PR2 9, United Kingdom
Scunthorpe General Hospital, Dept of Oncology
Scunthorpe , DN15 , United Kingdom
Royal Marsden Academic Urology Unit
Sutton , SM2 5, United Kingdom
Clatterbridge Centre For Oncology
Wirral , CH63 , United Kingdom
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How clear is this clinincal trial information?

Study is for people with:

Prostate Cancer

Phase:

Phase 3

Estimated Enrollment:

408

Study ID:

NCT00133224

Recruitment Status:

Terminated

Sponsor:


Cell Genesys

How clear is this clinincal trial information?

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