Prostate Cancer Clinical Trial
Gallium Ga 68-DOTATATE PET/CT in Diagnosing Patients With Metastatic Castration Resistant Prostate Cancer
Summary
This pilot clinical trial studies how well gallium Ga 68-DOTATATE positron emission tomography (PET)/computed tomography (CT) works in treating patients with castration resistant prostate cancer that has spread to other placed in the body. Gallium Ga 68-DOTATATE PET/CT may help doctors to identify those patients with early neuroendocrine transdifferentiation and who are at greater risk for poor outcomes.
Full Description
PRIMARY OBJECTIVE:
Establish the feasibility of using gallium Ga 68-DOTATATE (68Ga-DOTATATE) PET as a predictive imaging biomarker for neuroendocrine transdifferentiation in prostate cancer.
SECONDARY OBJECTIVE:
Correlate progression of disease with degree of uptake on 68Ga-DOTATATE PET examination.
OUTLINE:
Patients receive gallium Ga 68-DOTATATE intravenously (IV). Within 55-70 minutes, patients undergo PET/CT.
After completion of study, patients are followed up for at least 1 year.
Eligibility Criteria
Inclusion Criteria:
Patients with metastatic castration resistant prostate carcinoma with skeletal, visceral and/or nodal involvement
Ability to lie still for PET scanning
Patients must be able to provide written informed consent
Exclusion Criteria:
Patients less than 18 years of age
Patients without metastatic castration resistant prostate carcinoma with skeletal, visceral and/or nodal involvement
Inability to lie still for PET scanning
Patients unable to provide written informed consent
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There is 1 Location for this study
Atlanta Georgia, 30322, United States
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