Lycopene In Preventing of Prostate Cancer

DISEASE CHARACTERISTICS:

Normal healthy males judged to be in good medical condition based on history and physical exam confirming the absence of chronic medical conditions
Baseline serum lycopene less than 600 nM

PATIENT CHARACTERISTICS:

Age:

18 to 45

Performance status:

Karnofsky 100%

Life expectancy:

Not specified

Hematopoietic:

Hematologic function normal

Hepatic:

Liver function normal
No hepatic disease

Renal:

Kidney function normal
No renal disease

Cardiovascular:

No hypertension requiring medication
No cardiovascular disease
Normal EKG

Other:

No evidence of a psychiatric disorder
Must be within 15% of ideal body weight based on standard weight tables
No history of smoking within the past 3 months
At least 72 hours since prior alcohol consumption and no history of alcohol abuse
No history of gastrointestinal malabsorption or any other condition that could affect drug absorption
No allergy to tomato based products
No active malignancy at any site
No illness that would pose a threat or additional risk (e.g., thyroid disease, diabetes mellitus)

PRIOR CONCURRENT THERAPY:

Biologic therapy:

Not specified

Chemotherapy:

Not specified

Endocrine therapy:

Not specified

Radiotherapy:

Not specified

Surgery:

Not specified

Other:

At least 14 days since prior prescription drugs
No concurrent regular prescription medications
At least 30 days since other prior experimental drugs
No concurrent participation in any other experimental trial