Prostate Cancer Clinical Trial

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Prostate-specific Membrane Antigen Antibody-Drug Conjugate in Subjects With Prostate Cancer

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Summary

Prostate-specific Membrane Antigen Antibody-Drug Conjugate (PSMA ADC) 1301 is an open-label, dose-escalation phase 1 study of PSMA ADC administered IV in subjects with progressive, castration-resistant, metastatic prostate cancer that has progressed after prior taxane therapy. For all subjects, PSMA ADC will be administered in four repeating cycles.

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Eligibility Criteria

Inclusion Criteria:

A diagnosis of progressive, castration-resistant, metastatic prostate cancer.
Prior chemotherapy regimens, one of which contains taxane.
Eastern Cooperative Oncology Group status of 0 or 1

Exclusion Criteria:

Clinically significant cardiac disease or severe debilitation pulmonary disease
Evidence of an active infection requiring ongoing antibiotic therapy
Any prior treatment with any other therapy targeting PSMA
History of drug and/or alcohol abuse

Study is for people with:

Prostate Cancer

Phase:

Phase 1

Estimated Enrollment:

52

Study ID:

NCT01414283

Recruitment Status:

Completed

Sponsor:

Progenics Pharmaceuticals, Inc.

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There is 1 Location for this study

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Progenics Pharmaceuticals, Inc.
Tarrytown New York, 10591, United States

How clear is this clinincal trial information?

Study is for people with:

Prostate Cancer

Phase:

Phase 1

Estimated Enrollment:

52

Study ID:

NCT01414283

Recruitment Status:

Completed

Sponsor:


Progenics Pharmaceuticals, Inc.

How clear is this clinincal trial information?

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