Prostate Cancer Clinical Trial

Soy Derivatives for Control of Hot Flashes in Men on Androgen Deprivation Therapy

Summary

To determine the efficacy of soy/isoflavone supplementation on hot flashes in men who are being treated with luteinizing hormone-releasing hormone (LHRH) agonist therapy for control of advanced prostate cancer

View Full Description

Full Description

Literature has shown that low dose estrogens can control hot flashes in men on androgen deprivation but with a high risk of thromboembolic events. Soy derivatives that contain isoflavones, a type of phytoestrogen, have been evaluated in peri-menopausal women as a possible safer alternative to synthetic estrogens but there has not been a similar study performed on their effect in men on androgen deprivation therapy for prostate cancer.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Histologically proven adenocarcinoma of prostate with treatment of prostate cancer (radical prostatectomy, radiation therapy, etc.)
had biochemical/clinical relapse and started on antiandrogens
have documented history of hot flashes

Exclusion Criteria:

History of MI, DVT, CVA
peanut allergy
untreated hypothyroidism
must be off other medical treatment for hot flashes for 2 weeks before enrollment in this study

Study is for people with:

Prostate Cancer

Phase:

Phase 2

Estimated Enrollment:

11

Study ID:

NCT00594620

Recruitment Status:

Terminated

Sponsor:

University of Kansas Medical Center

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

University of Kansas Medical Center
Kansas City Kansas, 66160, United States

How clear is this clinincal trial information?

Study is for people with:

Prostate Cancer

Phase:

Phase 2

Estimated Enrollment:

11

Study ID:

NCT00594620

Recruitment Status:

Terminated

Sponsor:


University of Kansas Medical Center

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.

Please confirm you are a US based health care provider:

Yes, I am a health care Provider No, I am not a health care provider