Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer Summary The purpose of this study is to assess the safety, tolerability and preliminary efficacy of CC-94676 in men with progressive metastatic castration resistant prostate cancer .
View Eligibility Criteria Eligibility Criteria Inclusion Criteria: Must have histologically or cytologically confirmed adenocarcinoma of the prostate Progressed on androgen deprivation therapy (ADT) and at least one prior secondary hormonal therapy approved for castration-resistant prostate cancer (CRPC) Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0 or 1 Exclusion Criteria: Prior treatment with an androgen receptor (AR) degrader Concurrent malignancy (present during screening) requiring treatment or history of prior malignancy active within 1 year prior to the first dose of IP Clinically significant venous thromboembolism within 3 months prior to the first dose of IP Any significant medical condition, such as uncontrolled infection, laboratory abnormality, or psychiatric illness Other protocol-defined inclusion/exclusion criteria apply
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There are 24 Locations for this study
Local Institution - 118 Birmingham Alabama, 35249, United States
Stanford University Stanford California, 94305, United States
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Medstar Washington Hospital Center Washington District of Columbia, 20010, United States
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Sibley Memorial Hospital Washington District of Columbia, 20016, United States
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Florida Cancer Specialists Sarasota Florida, 34232, United States
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Emory University. Atlanta Georgia, 30303, United States
Lewis Hall Singletary Oncology Center Thomasville Georgia, 31792, United States
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University Of Chicago Chicago Illinois, 60637, United States
Johns Hopkins Baltimore Maryland, 21287, United States
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Dana Farber Cancer Institute Boston Massachusetts, 02215, United States
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University Of Michigan Cancer Center Ann Arbor Michigan, 48109, United States
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START Midwest Grand Rapids Michigan, 49546, United States
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Mount Sinai - Icahn School of Medicine New York New York, 10029, United States
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Mount Sinai Doctors Dermatology New York New York, 10029, United States
Columbia University New York New York, 10032, United States
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Memorial Sloan Kettering cancer Center New York New York, 10065, United States
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Duke University Medical Center Durham North Carolina, 27710, United States
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Lehigh Valley Health Network Allentown Pennsylvania, 18103, United States
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Abramson Cancer Center Philadelphia Pennsylvania, 19104, United States
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Abramson Cancer Center Philadelphia Pennsylvania, 19104, United States
Ut Southwestern Dallas Texas, 75235, United States
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M.D. Anderson Cancer Center Houston Texas, 77030, United States
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South Texas Accelerated Research Therapeutics (START) San Antonio Texas, 78229, United States
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Fred Hutchinson Cancer Center Seattle Washington, 98109, United States
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University of Wisconsin Carbone Cancer Center Madison Wisconsin, 53705, United States
University of Wisconsin Carbone Cancer Center Madison Wisconsin, 53792, United States
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University of Wisconsin Carbone Cancer Center Madison Wisconsin, 53792, United States
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