Prostate Cancer Clinical Trial
The Effect of Deep Versus Moderate Muscle Relaxants in Men During and After Robotic Surgery for Prostate Cancer
Summary
The purpose of this study is to determine if there is a difference in intra-abdominal pressure which surgeons use during surgery and post-surgery pain in men who undergo robotic prostate surgery with deep neuromuscular blockade (NMB), compared with moderate NMB.
Eligibility Criteria
Inclusion Criteria:
Adult patients under the age of 80
American Society of Anesthesiologists Physical Status 1, 2, 3.
Elective Robotic Prostatectomy
Patient undergoing surgery at Josie Robertson Surgical Center
Exclusion Criteria:
Age younger than 18
Inability to provide informed consent
Allergy to rocuronium, sugammadex, midazolam, propofol, fentanyl, lidocaine, mannitol (IV Acetaeminophen), IV Acetaminophen, Ketorolac, Morphine, Hydromorphone, Dexamethasone, Zofran, Benadryl, Compazine
Neuromuscular disease
Any patient with previous abdominal surgery less than or equal to 20 years prior to scheduled surgery date
Patients with BMI>35
Severe renal impairment (Creatinine clearance < 30 ml/min)
Patient receiving Toremifene or any history of receiving Toremifene
Chronic pain patients
Patients receiving suboxone
Patients receiving succinylcholine
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