Psoriasis Clinical Trial

A Study of Ixekizumab in Participants With Active Psoriatic Arthritis

Summary

This study will assess the safety and efficacy of ixekizumab (LY2439821) compared to placebo in participants with active psoriatic arthritis.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Presents with established diagnosis of active psoriatic arthritis for at least 6 months, and currently meets Classification for Psoriatic Arthritis (CASPAR) criteria
Active psoriatic arthritis (PsA) defined as the presence of at least 3 tender and at least 3 swollen joints
Presence of active psoriatic skin lesion or a personal history of plaque psoriasis (Ps)
Men must agree to use a reliable method of birth control or remain abstinent during the study
Women must agree to use reliable birth control or remain abstinent during the study and for at least 12 weeks after stopping treatment

Exclusion Criteria:

Current or prior use of biologic agents for treatment of Ps or PsA
Inadequate response to greater than or equal to 4 conventional disease-modifying antirheumatic drugs (DMARDs)
Current use of more than one conventional DMARD
Evidence of active inflammatory arthritic syndromes or spondyloarthropathies other than PsA
Have participated in any study with interleukin 17 (IL-17) antagonists, including ixekizumab
Serious disorder or illness other than psoriatic arthritis
Serious infection within the last 3 months
Breastfeeding or nursing (lactating) women

Study is for people with:

Psoriasis

Phase:

Phase 3

Estimated Enrollment:

417

Study ID:

NCT01695239

Recruitment Status:

Completed

Sponsor:

Eli Lilly and Company

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There are 116 Locations for this study

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Birmingham Alabama, 35205, United States
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Huntsville Alabama, 35801, United States
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Tuscaloosa Alabama, 35406, United States
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Little Rock Arkansas, 72205, United States
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Upland California, 91786, United States
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Trumbull Connecticut, 06611, United States
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Boca Raton Florida, 33486, United States
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Orange Park Florida, 32073, United States
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Tampa Florida, 33614, United States
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Zephyrhills Florida, 33542, United States
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Atlanta Georgia, 30342, United States
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Decatur Georgia, 30033, United States
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Marietta Georgia, 30060, United States
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Indianapolis Indiana, 46227, United States
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Cedar Rapids Iowa, 52403, United States
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Wichita Kansas, 67207, United States
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Cumberland Maryland, 21502, United States
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Hagerstown Maryland, 21740, United States
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Saint Louis Missouri, 63141, United States
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Toms River New Jersey, 08753, United States
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Voorhees New Jersey, 08043, United States
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Brooklyn New York, 11201, United States
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Rochester New York, 14642, United States
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Charlotte North Carolina, 28210, United States
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Durham North Carolina, 27704, United States
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Greensboro North Carolina, 27408, United States
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Dayton Ohio, 45417, United States
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Duncansville Pennsylvania, 16635, United States
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Columbia South Carolina, 29204, United States
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Orangeburg South Carolina, 29118, United States
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Jackson Tennessee, 38305, United States
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Dallas Texas, 75231, United States
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Houston Texas, 77062, United States
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Kennewick Washington, 99336, United States
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Seattle Washington, 98122, United States
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Spokane Washington, 99204, United States
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Clarksburg West Virginia, 26301, United States
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Genk , 3600, Belgium
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Gent , 9000, Belgium
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Liège , 4000, Belgium
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Pleven , 5800, Bulgaria
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Plovdiv , 4002, Bulgaria
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Sliven , 8800, Bulgaria
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Sofia , 1233, Bulgaria
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Stara Zagora , 6000, Bulgaria
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Ottawa Ontario, K1H 1, Canada
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Toronto Ontario, M5T2S, Canada
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Waterloo Ontario, N2J 1, Canada
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Quebec , G1V3M, Canada
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Brno , 638 0, Czechia
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Bruntal , 79201, Czechia
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Hlucin , 748 0, Czechia
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Ostrava - Trebovice , 722 0, Czechia
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Prague , 15800, Czechia
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Zlin , 760 0, Czechia
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Tallinn , 13419, Estonia
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Bordeaux , 33076, France
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Nantes , 44093, France
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Orleans , 45032, France
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Toulouse , 31059, France
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Fukuoka , 810-8, Japan
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Hokkaido , 078-8, Japan
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Okayama , 700-8, Japan
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Osaka , 545-8, Japan
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Tokyo , 160-8, Japan
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Chihuahua , 31238, Mexico
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Guadalajara , 45040, Mexico
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Mexico City , 06700, Mexico
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Monterrey , 64000, Mexico
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San Luis Potosi , 78213, Mexico
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Almelo , 7600S, Netherlands
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Amsterdam , 1105 , Netherlands
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Maastricht , 6229 , Netherlands
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Nijmegen , 6522 , Netherlands
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Rotterdam , 3079 , Netherlands
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Sneek , 8601 , Netherlands
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Bialystok , 158-7, Poland
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Katowice , 40-63, Poland
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Krakow , 31-50, Poland
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Lublin , 20-58, Poland
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Poznan , 60-53, Poland
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Sroda Wielkopolska , 63-00, Poland
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Warsaw , 02-11, Poland
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Wroclaw , 51-12, Poland
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Barnaul , 65602, Russian Federation
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Ekaterinburg , 62010, Russian Federation
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Kazan , 42009, Russian Federation
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Moscow , 11552, Russian Federation
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Petrozavodsk , 18501, Russian Federation
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Saint Petersburg , 19325, Russian Federation
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Barcelona , 08034, Spain
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Bilbao , 48013, Spain
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Cordoba , 14004, Spain
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Majadahonda , 28222, Spain
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Málaga , 29009, Spain
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Sabadell , 08208, Spain
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Santander , 39008, Spain
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Sevilla , 41009, Spain
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Dnipropetrovsk , 49044, Ukraine
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Donetsk , 83045, Ukraine
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Ivano-Frankivsk , 76008, Ukraine
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Kharkiv , 61176, Ukraine
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Kyiv , 03680, Ukraine
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Lutsk , 43024, Ukraine
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Lviv , 79011, Ukraine
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Odesa , 65026, Ukraine
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Vinnytsia , 21029, Ukraine
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Zaporizhzhia , 69600, Ukraine
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Cambridge Cambridgeshire, CB2 0, United Kingdom
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Goodmayes Essex, IG7 4, United Kingdom
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London Greater London, E11 1, United Kingdom
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Headington Oxford, OX3 7, United Kingdom
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Wolverhampton West Midlands, WV10 , United Kingdom
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Bradford West Yorkshire, BD5 0, United Kingdom
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Leeds West Yorkshire, LS7 4, United Kingdom
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Liverpool , L9 7A, United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Phase 3

Estimated Enrollment:

417

Study ID:

NCT01695239

Recruitment Status:

Completed

Sponsor:


Eli Lilly and Company

How clear is this clinincal trial information?

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