Psoriasis Clinical Trial

A Study of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas (Scalp, Genital, and/or Palms of the Hands and the Soles of the Feet)

Summary

The purpose of the study is to see how effective JNJ-77242113 is in participants with plaque psoriasis affecting special areas (scalp, genital, and/or palms of the hands and the soles of the feet).

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Diagnosis of plaque psoriasis, with or without psoriatic arthritis (PsA), for at least 26 weeks prior to the first administration of study intervention
Candidate for phototherapy or systemic treatment for plaque psoriasis
Need to meet criteria: Total body surface area (BSA) greater than or equal to (>=)1 percent (%) at screening and baseline, and investigator global assessment (IGA) (overall) >=2 at screening and baseline and at least one of the following: scalp-specific investigator global assessment (ss-IGA) score >=3 at screening and baseline, and/or static physician's global assessment of genitalia (sPGA-G) >=3 at screening and baseline, and/or physician's global assessment of hands and feet (hf-PGA) score >=3 at screening and baseline
Failed to respond to at least 1 topical therapy (example, corticosteroids, calcineurin inhibitors, and/or vitamin D analogs) used for treatment of psoriasis
Confirmation of plaque psoriasis in a non-special area (example, areas excluding scalp, genital, palmoplantar) at screening and baseline

Exclusion Criteria:

Nonplaque form of psoriasis (example, erythrodermic, guttate, or pustular)
Dermatoses other than plaque psoriasis (such as contact dermatitis) or palmoplantar pustulosis of the palmoplantar area (if hf-PGA >=3 at baseline)
Current drug-induced psoriasis (example, a new onset of psoriasis or an exacerbation of psoriasis from beta blockers, calcium channel blockers, or lithium)
A current diagnosis or signs or symptoms of severe, progressive, or uncontrolled renal, liver, cardiac, vascular, pulmonary, gastrointestinal, endocrine, neurologic, hematologic, rheumatologic, psychiatric, or metabolic disturbances
Known allergies, hypersensitivity, or intolerance to JNJ-77242113 or its excipients

Study is for people with:

Psoriasis

Phase:

Phase 3

Estimated Enrollment:

300

Study ID:

NCT06095102

Recruitment Status:

Recruiting

Sponsor:

Janssen Research & Development, LLC

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There are 17 Locations for this study

See Locations Near You

Johnson Dermatology
Fort Smith Arkansas, 72916, United States
Hamilton Research, LLC.
Alpharetta Georgia, 30022, United States
Arlington Dermatology
Rolling Meadows Illinois, 60008, United States
Indiana Clinical Trial Center
Plainfield Indiana, 46168, United States
Dermatology and Advanced Aesthetics
Lake Charles Louisiana, 70605, United States
Hamzavi Dermatology
Fort Gratiot Michigan, 48059, United States
Minnesota Clinical Study Center
New Brighton Minnesota, 55112, United States
MediSearch Clinical Trials
Saint Joseph Missouri, 64506, United States
Skin Specialists
Omaha Nebraska, 68144, United States
Windsor Dermatology
East Windsor New Jersey, 08520, United States
Optima Research
Boardman Ohio, 44512, United States
Oregon Dermatology and Research Center
Portland Oregon, 97210, United States
Arlington Research Center, Inc.
Arlington Texas, 76011, United States
Austin Institute for Clinical Research
Pflugerville Texas, 78660, United States
Progressive Clinical Research
San Antonio Texas, 78213, United States
Frontier Derm Partners CRO, LLC
Mill Creek Washington, 98012, United States
National Taiwan University Hospital
Taipei , 10048, Taiwan

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Phase 3

Estimated Enrollment:

300

Study ID:

NCT06095102

Recruitment Status:

Recruiting

Sponsor:


Janssen Research & Development, LLC

How clear is this clinincal trial information?

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