Psoriasis Clinical Trial

A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis

Summary

The purpose of this study is see how effective is JNJ-77242113 in participants with moderate to severe plaque psoriasis.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Diagnosis of plaque psoriasis, with or without psoriatic arthritis, for at least 26 weeks prior to the first administration of study intervention
Total body surface area (BSA) greater than or equal to (>=)10 percent (%) at screening and baseline
Total psoriasis area and severity index (PASI) >=12 at screening and baseline
Total investigator global assessment (IGA) >=3 at screening and baseline
Candidate for phototherapy or systemic treatment for plaque psoriasis
A female participant of childbearing potential must have a negative highly sensitive serum pregnancy test beta-human chorionic gonadotropin (beta-hCG) at screening and a negative urine pregnancy test at Week 0 prior to administration of study intervention

Exclusion Criteria:

Nonplaque form of psoriasis (for example, erythrodermic, guttate, or pustular)
Current drug-induced psoriasis (for example, a new onset of psoriasis or an exacerbation of psoriasis from beta blockers, calcium channel blockers, or lithium)
A current diagnosis or signs or symptoms of severe, progressive, or uncontrolled renal, liver, cardiac, vascular, pulmonary, gastrointestinal, endocrine, neurologic, hematologic, rheumatologic, psychiatric, or metabolic disturbances
Known allergies, hypersensitivity, or intolerance to JNJ-77242113 or its excipients
Major surgical procedures, (for example, requiring general anesthesia) within 8 weeks before screening, or will not have fully recovered from a surgical procedure or has a surgical procedure planned during the time the participant is expected to participate in the study

Study is for people with:

Psoriasis

Phase:

Phase 3

Estimated Enrollment:

684

Study ID:

NCT06095115

Recruitment Status:

Active, not recruiting

Sponsor:

Janssen Research & Development, LLC

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There are 170 Locations for this study

See Locations Near You

Medical Dermatology Specialists
Phoenix Arizona, 85006, United States
Johnson Dermatology
Fort Smith Arkansas, 72916, United States
First OC Dermatology
Fountain Valley California, 92708, United States
Center for Dermatology Clinical Research
Fremont California, 94538, United States
Integrative Skin Science and Research
Sacramento California, 95815, United States
Rady Childrens Hospital San Diego
San Diego California, 92123, United States
Southern California Dermatology
Santa Ana California, 92701, United States
Clinical Science Institute
Santa Monica California, 90404, United States
Bioclinical Research Alliance Inc.
Miami Florida, 33155, United States
Ziaderm Research, LLC
North Miami Beach Florida, 33162, United States
Forcare Clinical Research Inc
Tampa Florida, 33613, United States
Skin Care Physicians of Georgia
Macon Georgia, 31217, United States
Arlington Dermatology
Rolling Meadows Illinois, 60008, United States
Northshore Medical Group
Skokie Illinois, 60077, United States
Dundee Dermatology
West Dundee Illinois, 60118, United States
Dawes Fretzin Clinical Research Group, LLC
Indianapolis Indiana, 46250, United States
Indiana Clinical Trial Center
Plainfield Indiana, 46168, United States
Qualmedica Research
Owensboro Kentucky, 42301, United States
Dermatology and Advanced Aesthetics
Lake Charles Louisiana, 70605, United States
Allcutis Research
Beverly Massachusetts, 01915, United States
Michigan Center of Medical Research
Clarkston Michigan, 48346, United States
Minnesota Clinical Study Center
New Brighton Minnesota, 55112, United States
Skin Specialists
Omaha Nebraska, 68144, United States
Allcutis Research
Portsmouth New Hampshire, 03801, United States
Windsor Dermatology
East Windsor New Jersey, 08520, United States
Icahn School of Medicine at Mt. Sinai
New York New York, 10029, United States
Wilmington Dermatology Center
Wilmington North Carolina, 28405, United States
Oakview Dermatology
Athens Ohio, 45701, United States
Optima Research
Boardman Ohio, 44512, United States
Wright State Physicians Health Center
Fairborn Ohio, 45324, United States
Central Sooner Research
Oklahoma City Oklahoma, 73170, United States
Oregon Medical Research Center
Portland Oregon, 97201, United States
Oregon Dermatology and Research Center
Portland Oregon, 97210, United States
The Pennsylvania Centre for Dermatology, LLC
Exton Pennsylvania, 19341, United States
University of Pittsburgh Medical Center
Pittsburgh Pennsylvania, 15213, United States
Medical University of South Carolina
Charleston South Carolina, 29425, United States
Health Concepts
Rapid City South Dakota, 57702, United States
Arlington Research Center, Inc.
Arlington Texas, 76011, United States
The University of Texas Health Science Center at Houston
Bellaire Texas, 77401, United States
Center for Clinical Studies
Houston Texas, 77004, United States
Texas Dermatology and Laser Specialists
San Antonio Texas, 78218, United States
Center for Clinical Studies
Webster Texas, 77598, United States
Springville Dermatology CCT Research
Springville Utah, 84663, United States
Virginia Dermatology Skin Cancer Center Pllc
Norfolk Virginia, 23502, United States
Frontier Derm Partners CRO, LLC
Mill Creek Washington, 98012, United States
Premier Clinical Research
Spokane Washington, 99202, United States
CINME Metabolic Research Center
Buenos Aires , C1027, Argentina
Centro Privado de Medicina Familiar
Buenos Aires , C1417, Argentina
Psoriahue
Caba , C1425, Argentina
ARCIS Salud SRL Aprillus asistencia e investigacion
Ciudad Autonoma de Buenos Aires , C1406, Argentina
Centro de Investigaciones Medicas Mar Del Plata
Mar Del Plata , B7600, Argentina
Instituto De Especialidades De La Salud SRL
Rosario , S2000, Argentina
MR Medicina Reumatologica
San Fernando Buenos Aires , B1646, Argentina
Dr Rodney Sinclair Pty Ltd
East Melbourne , 3002, Australia
The Alfred Hospital
Melbourne , 3004, Australia
Kingsway Dermatology & Aesthetics
Miranda , 2228, Australia
ISHI dermatology
Mitcham , 3132, Australia
Royal Melbourne Hospital
Parkville , 3050, Australia
Veracity Clinical Research
Woolloongabba , 4102, Australia
Dermatology Research Institute Inc.
Calgary Alberta, T2J 7, Canada
Rejuvenation Dermatology Clinic Edmonton Downtown
Edmonton Alberta, T5J 3, Canada
Dr. Chih-ho Hong Medical
Surrey British Columbia, V3R 6, Canada
Mediprobe Research Inc.
London Ontario, N5X 2, Canada
Dr Wei Jing Loo Medicine Professional Corporation
London Ontario, N6H 5, Canada
Dr. Sk Siddha Medicine Professional Corporation
Newmarket Ontario, L3Y 5, Canada
Canadian Dermatology Center
Toronto Ontario, M3B 0, Canada
Toronto Research Centre
Toronto Ontario, M3H 5, Canada
FACET Dermatology
Toronto Ontario, M4C 1, Canada
XLR8 Medical Research
Windsor Ontario, N8T 1, Canada
Innovaderm Research Inc.
Montreal Quebec, H2X 2, Canada
China-Japan Friendship Hospital
Beijing , 10001, China
Beijing Friendship Hospital Capital Medical University
Beijing , 10005, China
Peking University Third Hospital
Beijing , 10019, China
The Affiliated Hospital of Bengbu Medical College
Bengbu , 23309, China
Hosp. of Chengde Medical University
Cheng De Shi , 06703, China
Chengdu Second People's Hospital
Chengdu , 61001, China
The First Hospital of Jiaxing
Jiaxing , 31400, China
Qilu Hospital of Shandong University
Jinan , 25001, China
Nanyang First People's Hospital
Nan Yang Shi , 47300, China
Dermatology Hospital of Jiangxi Province
NanChang , 33000, China
Shanghai skin disease hospital
Shanghai , 20044, China
Northeast International Hospital
Shen Yang , 11001, China
Union Hospital Tongji Medical College of Huazhong University of Science and Technology
Wuhan , 43002, China
The Second Affiliated Hospital of Xi'an Jiaotong University
Xi'an , 71000, China
Affiliated Hospital of Jiangsu University
Zhenjiang , 21200, China
Hopital Prive d'Antony
Antony , 92160, France
Centre Hospitalier Victor Dupouy
Argenteuil , 95107, France
Fachklinik Bad Bentheim
Bad Bentheim , 48455, Germany
Charite - Campus Mitte
Berlin , 10117, Germany
Universitatsklinikum Bonn
Bonn , 53127, Germany
Klinische Forschung Dresden GmbH
Dresden , 01069, Germany
Hautzentrum Dulmen
Dulmen , 48249, Germany
Privatpraxis Dr. Hilton & Partner
Dusseldorf , 40212, Germany
Universitaetsklinikum Frankfurt
Frankfurt am Main , 60590, Germany
Universitaetsklinikum Freiburg
Freiburg , 79104, Germany
Derma-Study-Center Friedrichshafen GmbH
Friedrichshafen , 88045, Germany
Universitaetsklinikum Heidelberg
Heidelberg , 69120, Germany
Hautarztpraxis
Mahlow , 15831, Germany
Universitaetsklinikum Muenster
Muenster , 48149, Germany
Klinikum Oldenburg
Oldenburg , 26133, Germany
Hautarztpraxis Mortazawi
Remscheid , 42897, Germany
Universitaetsklinik Tuebingen
Tubingen , 72076, Germany
Hautarztpraxis
Witten , 58453, Germany
CentroDerm GmbH
Wuppertal , 42287, Germany
Pecsi Tudomanyegyetem
Borgyogyaszati Klinika , 7632, Hungary
Obudai Egeszsegugyi Centrum Kft
Budapest , 1036, Hungary
Derma-B Kft
Debrecen , 4031, Hungary
Debreceni Egyetem Klinikai Kozpont
Debrecen , 4032, Hungary
Somogy Varmegyei Kaposi Mor Oktato Korhaz
Kaposvar , 7400, Hungary
SZTE AOK Szent-Gyorgyi Albert Klinikai Kozpont, Borgyogyaszati és Allergologiai Klinika
Szeged , 6720, Hungary
Allergo-Derm Bakos Kft.
Szolnok , 5000, Hungary
Medmare Egeszsegugyi Es Szolgaltato Bt.
Veszprem , 8200, Hungary
Azienda Di Rilievo Nazionale E Di Alta Specializzazione
Palermo , 90127, Italy
Azienda Ospedaliero Universitaria di Parma
Parma , 43126, Italy
Policlinico Tor Vergata
Roma , 00133, Italy
Istituto Clinico Humanitas
Rozzano , 20089, Italy
Teikyo University Hospital
Itabashi Ku , 173 8, Japan
Hospital of the University of Occupational and Environmental Health
Kitakyushu-shi , 807-8, Japan
Mito Kyodo General Hospital
Mito , 310 0, Japan
Nagoya City University Hospital
Nagoya , 467 8, Japan
Kindai University Hospital
Osaka Sayama shi , 589 8, Japan
Tohoku University Hospital
Sendai , 980 8, Japan
Tokyo Medical University Hospital
Shinjuku , 160-0, Japan
Mie University Hospital
Tsu , 514 8, Japan
Korea University Ansan Hospital
Ansan-si , 15355, Korea, Republic of
Chosun university hospital
Gwangju , 61453, Korea, Republic of
CHA Bundang Medical Center, CHA University
Gyeonggi-do , 13496, Korea, Republic of
Hallym University Sacred Heart Hospital
Gyeonggi-do , 14068, Korea, Republic of
Asan Medical Center
Seoul , 05505, Korea, Republic of
Specderm Poznanska sp j
Bialystok , 15 37, Poland
Osteo-Medic s.c A. Racewicz, J Supronik
Bialystok , 15-35, Poland
Centrum Kliniczno Badawcze J. Brzezicki, B. Gornikiewicz-Brzezicka Lekarze Spolka Partnerska
Elblag , 82-30, Poland
Specjalistyczny gabinet dermatologiczny Aplikacyjno Badawczy Marek Brzewski Pawel Brzewski Spolka Cywilna
Krakow , 30 00, Poland
Centrum Medyczne dr Rajzer Spolka z ograniczona dzialalnoscia
Krakow , 30 43, Poland
Centrum Medyczne Promed
Krakow , 31-41, Poland
Dermed Centrum Medyczne Sp z o o
Lodz , 90 26, Poland
Centrum Terapii Wspolczesnej J M Jasnorzewska Spolka Komandytowo Akcyjna
Lodz , 90-33, Poland
DermoDent Centrum Medyczne Aldona Czajkowska Rafał Czajkowski s.c.
Osielsko , 86031, Poland
SOLUMED Centrum Medyczne
Poznan , 60-52, Poland
Clinical Research Center sp z o o MEDIC R s k
Poznan , 61 73, Poland
Przychodnia Specjalistyczna High Med
Warszawa , 01-81, Poland
Klinika Ambroziak Dermatologia
Warszawa , 02-95, Poland
DERMMEDICA Sp.z o.o.
Wroclaw , 51 50, Poland
Centrum Medyczne Oporow
Wroclaw , 52-41, Poland
WroMedica I.Bielicka, A.Strzałkowska s.c.
Wrocław , 51-68, Poland
Hosp. Univ. Fundacion Alcorcon
Alcorcon , 28922, Spain
Hosp. Gral. Univ. Dr. Balmis
Alicante , 03010, Spain
Hosp. Clinic de Barcelona
Barcelona , 08036, Spain
Hosp. de La Santa Creu I Sant Pau
Barcelona , 08041, Spain
Hosp. Univ. de Basurto
Bilbao , 48013, Spain
Grupo Dermatologico Y Estetico Pedro Jaen
Madrid , 28006, Spain
Hosp. Gral. Univ. Gregorio Maranon
Madrid , 28007, Spain
Hosp. Univ. Son Espases
Palma de Mallorca , 07120, Spain
Hosp. Clinico Univ. de Santiago
Santiago de Compostela , 15706, Spain
Hosp. Virgen Macarena
Sevilla , 41009, Spain
Hosp. de Manises
Valencia , 46940, Spain
National Taiwan University Hospital Hsin-Chu Branch
Hsin Chu , 30059, Taiwan
Kaohsiung Chang Gung Memorial Hospital
Kaohsiung , 83301, Taiwan
National Taiwan University Hospital
Taipei , 10048, Taiwan
Mackay Memorial Hospital
Taipei , 10449, Taiwan
Taipei Veterans General Hospital
Taipei , 11217, Taiwan
Linkou Chang Gung Memorial Hospital
Taoyuan , 33382, Taiwan
Hacettepe University Medical Faculty
Ankara , 06230, Turkey
Gazi University Medical Faculty
Ankara , 06560, Turkey
Erciyes University Medical Faculty
Kayseri , 38039, Turkey
Ondokuz Mayis University
Samsun , 55270, Turkey
London North West University Healthcare NHS Trust
Harrow , HA1 3, United Kingdom
Guy's and St Thomas' NHS Foundation Trust
London , SE1 9, United Kingdom
Royal Berkshire Hospital
Reading , RG1 5, United Kingdom
Salford Royal Hospital
Salford , M6 8H, United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Phase 3

Estimated Enrollment:

684

Study ID:

NCT06095115

Recruitment Status:

Active, not recruiting

Sponsor:


Janssen Research & Development, LLC

How clear is this clinincal trial information?

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