Psoriasis Clinical Trial

A Study of Ruxolitinib Phosphate Cream When Applied to Patients With Plaque Psoriasis

Summary

The study is comprised of two parts. The first portion of this study will be a double-blind, Sponsor-unblinded, vehicle-controlled study with application of ruxolitinib or vehicle to paired lesions at least 15 cm apart in patients with active but stable plaque psoriasis. Part 2 of the study is a double-blind, sponsor unblinded, comparison of ruxolitinib with two FDA approved products in patients with active but stable plaque psoriasis.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Body Mass Index (BMI) of 17 to 40 kg/m2
Subjects must have two comparable psoriatic lesions measuring between 9 and 100 cm2 and these target lesions must be similar in size to each other, and separated by at least 15 cm.

Exclusion Criteria:

Subjects with lesions solely involving the palms of the hands or soles of the feet or intertriginous areas, the scalp or the face.
Subjects with pustular psoriasis or erythroderma.
Subjects currently on other topical agents or UVB therapy within 2 weeks of the first dose of study medication.
Subjects receiving PUVA within 4 weeks of the first dose of study medication.
Subjects receiving systemic retinoids, etanercept, adalimumab or efalizumab or oral immunosuppressives within 3 months prior to the first dose of study medication.
Subjects receiving any other biological therapy (infliximab, alefacept, abatacept, etc) within 3 months of the first dose of study medication.

Study is for people with:

Psoriasis

Phase:

Phase 2

Estimated Enrollment:

29

Study ID:

NCT00820950

Recruitment Status:

Completed

Sponsor:

Incyte Corporation

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There is 1 Location for this study

See Locations Near You


Vallejo California, , United States

Boston Massachusetts, , United States

Rochester New York, , United States

Stony Brook New York, , United States

Portland Oregon, , United States

Philadelphia Pennsylvania, , United States

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Phase 2

Estimated Enrollment:

29

Study ID:

NCT00820950

Recruitment Status:

Completed

Sponsor:


Incyte Corporation

How clear is this clinincal trial information?

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