Efficacy and Safety of Deucravacitinib Versus Placebo in Participants With Moderate-to-severe Scalp Psoriasis Summary The purpose of this study is to compare the efficacy and safety of deucravacitinib to placebo in participants with moderate-to-severe scalp psoriasis.
View Eligibility Criteria Eligibility Criteria Inclusion Criteria: Men and women diagnosed with stable plaque psoriasis with scalp involvement for 6 months or more. Stable psoriasis is defined as no morphology changes or significant flares of disease activity in the opinion of the Investigator Deemed by the Investigator to be a candidate for phototherapy or systemic therapy Scalp-specific Physician's Global Assessment (ss-PGA) ≥ 3; ≥ 20% scalp surface area (SSA); Psoriasis Scalp Severity Index (PSSI) ≥ 12 at Screening visit and Day 1 ≥ 3% of Body Surface Area (BSA) involvement at Screening visit and Day 1 Evidence of plaque psoriasis in a non-scalp area Failed to respond to, or intolerant of ≥ 1 topical therapy for scalp psoriasis Exclusion Criteria: Target Disease Exceptions: Has nonplaque psoriasis (ie, guttate, inverse, pustular, erythrodermic or drug-induced psoriasis) at Screening or Day 1 Other protocol-defined inclusion/exclusion criteria apply
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There are 34 Locations for this study
Burke Pharmaceutical Research Hot Springs Arkansas, 71913, United States
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Keck School of Medicine of University of Southern California Los Angeles California, 90033, United States
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Dawes Fretzin Clinical Research Group, LLC Indianapolis Indiana, 46250, United States
Dawes Fretzin Clinical Research Group, LLC Indianapolis Indiana, 46256, United States
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Skin Sciences, PLLC Louisville Kentucky, 40217, United States
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Lawrence J. Green, MD. LLC Rockville Maryland, 20850, United States
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ALLCUTIS Research, LLC Beverly Massachusetts, 01915, United States
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Henry Ford Medical Center - Bloomfield Hills Michigan, 48302, United States
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Minnesota Clinical Study Center Fridley Minnesota, 55432, United States
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Psoriasis Treatment Center of Central NJ East Windsor New Jersey, 08520, United States
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Forest Hill Dermatology Group Kew Gardens New York, 11415, United States
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Wake Forest University Health Sciences Winston-Salem North Carolina, 27157, United States
Oregon Medical Research Center Portland Oregon, 97223, United States
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UPMC Department of Dermatology Pittsburgh Pennsylvania, 15213, United States
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Center for Clinical Studies Houston Texas, 77004, United States
Center for Clinical Studies Houston Texas, 77004, United States
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Dermatology Clinical Research Center of San Antonio San Antonio Texas, 78229, United States
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University of Utah MidValley Dermatology Murray Utah, 84107, United States
Virginia Clinical Research , Inc Norfolk Virginia, 23502, United States
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Local Institution - 0019 Paris , 75010, France
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Local Institution - 0040 Romans sur Isere Cedex , 26102, France
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Local Institution - 0044 Rouen , 76031, France
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Local Institution - 0035 Mahlow Brandenburg, 15831, Germany
Local Institution - 0038 Witten Deutschland, 58454, Germany
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Local Institution - 0013 Frankfurt Hessen, 60590, Germany
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Local Institution - 0050 Luebeck Schleswig-Holstein, 23538, Germany
Local Institution - 0048 Hamburg , 20246, Germany
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Local Institution - 0012 Kiel , 24105, Germany
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Local Institution - 0011 Mahlow , 15831, Germany
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Local Institution - 0037 Lodz Woj.Lodzkie, 90-43, Poland
Local Institution - 0046 Lodz Woj.Lodzkie, 90-43, Poland
Local Institution - 0026 Krakow , 30438, Poland
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Local Institution - 0017 Lodz , 90-43, Poland
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Local Institution - 0014 Rzeszow , 35-00, Poland
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Local Institution - 0027 Rzeszow , 35-00, Poland
Local Institution - 0015 Wroclaw , 51-68, Poland
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Local Institution - 0036 Wroclaw , 51-68, Poland
Local Institution - 0031 London Greater London, SE1 9, United Kingdom
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Local Institution - 0045 Salford Greater Manchester, M6 8H, United Kingdom
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Local Institution - 0039 Southampton Hampshire, SO16 , United Kingdom
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