Psoriasis Clinical Trial
Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index
Summary
The object of this research study is to examine these associations in children as very little is known about psoriasis and cardiovascular risk factors in the pediatric population.
Full Description
Several environmental factors and comorbid conditions have been found to be associated with psoriasis in adults, including obesity, depression, smoking, and other cardiovascular risk factors such as high blood pressure. The object of this research study is to examine these associations in children as very little is known about psoriasis and cardiovascular risk factors in the pediatric population.
This is a multi-center study with a planned total enrollment of about 200 subjects ages 2-17 years old with psoriasis and 100 aged-match controls. Patient and family history will be recorded. All subjects will undergo standard height, weight, blood pressure, and waist circumference (WC). For the obese and overweight subjects we will also obtain their growth charts to attempt to correlate weight gain with psoriasis onset and progression. All data will be compiled and then statistically analyzed.
Eligibility Criteria
Inclusion Criteria:
Subjects must be between the ages of 5 and 17 years at the time of enrollment.
Subjects of either sex.
Subjects who have had psoriatic plaques for more than 6 months.
Subjects and guardians of minors must sign the approved IRB consent form(s) prior to initiation of the study protocol.
Subjects enrolled as "non-inflammatory" normal controls will carry a common non- systemic skin condition, such as acne, nevi, warts and molluscum as their main diagnosis.
Subjects enrolled as "inflammatory" normal controls will carry a diagnosis of moderate to severe atopic dermatitis.
Exclusion Criteria:
Subjects who are unable to give informed consent or assent.
Subjects who have had psoriasis for less than 6 months.
Subjects whose condition is deemed unsafe or incapable by the study investigator for study participation.
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There are 9 Locations for this study
San Diego California, 92123, United States
San Francisco California, 94143, United States
Stanford California, 94305, United States
Chicago Illinois, 60611, United States
Worcester Massachusetts, 01605, United States
St. Louis Missouri, 63117, United States
Cleveland Ohio, 44106, United States
Dallas Texas, 75246, United States
Houston Texas, 77030, United States
St. John's Newfoundland and Labrador, , Canada
Santiago , , Chile
Tuen Mun , , Hong Kong
Verona , , Italy
Nijmegen , , Netherlands
How clear is this clinincal trial information?

Please confirm you are a US based health care provider:
Yes, I am a health care Provider No, I am not a health care providerSign Up Now.
Take Control of Your Disease Journey.
Sign up now for expert patient guides, personalized treatment options, and cutting-edge insights that can help you push for the best care plan.