Psoriasis Clinical Trial

Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index

Summary

The object of this research study is to examine these associations in children as very little is known about psoriasis and cardiovascular risk factors in the pediatric population.

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Full Description

Several environmental factors and comorbid conditions have been found to be associated with psoriasis in adults, including obesity, depression, smoking, and other cardiovascular risk factors such as high blood pressure. The object of this research study is to examine these associations in children as very little is known about psoriasis and cardiovascular risk factors in the pediatric population.

This is a multi-center study with a planned total enrollment of about 200 subjects ages 2-17 years old with psoriasis and 100 aged-match controls. Patient and family history will be recorded. All subjects will undergo standard height, weight, blood pressure, and waist circumference (WC). For the obese and overweight subjects we will also obtain their growth charts to attempt to correlate weight gain with psoriasis onset and progression. All data will be compiled and then statistically analyzed.

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Eligibility Criteria

Inclusion Criteria:

Subjects must be between the ages of 5 and 17 years at the time of enrollment.
Subjects of either sex.
Subjects who have had psoriatic plaques for more than 6 months.
Subjects and guardians of minors must sign the approved IRB consent form(s) prior to initiation of the study protocol.
Subjects enrolled as "non-inflammatory" normal controls will carry a common non- systemic skin condition, such as acne, nevi, warts and molluscum as their main diagnosis.
Subjects enrolled as "inflammatory" normal controls will carry a diagnosis of moderate to severe atopic dermatitis.

Exclusion Criteria:

Subjects who are unable to give informed consent or assent.
Subjects who have had psoriasis for less than 6 months.
Subjects whose condition is deemed unsafe or incapable by the study investigator for study participation.

Study is for people with:

Psoriasis

Estimated Enrollment:

409

Study ID:

NCT00879944

Recruitment Status:

Completed

Sponsor:

Northwestern University

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There are 9 Locations for this study

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University of California, San Diego
San Diego California, 92123, United States
University of California, San Francisco
San Francisco California, 94143, United States
Stanford University School of Medicine
Stanford California, 94305, United States
Ann & Robert H Lurie Children's Hospital of Chicago
Chicago Illinois, 60611, United States
UMass Memorial Dermatology Center
Worcester Massachusetts, 01605, United States
Central Dermatology
St. Louis Missouri, 63117, United States
University Hospitals, Case Medical Centers
Cleveland Ohio, 44106, United States
Texas Dermatology Associates
Dallas Texas, 75246, United States
Texas Children's Hospital
Houston Texas, 77030, United States
Nexus Clinical Resarch
St. John's Newfoundland and Labrador, , Canada
Pontificia Universidad Catolica de Chile
Santiago , , Chile
University of Hong Kong
Tuen Mun , , Hong Kong
Universita Verona
Verona , , Italy
UMC St. Radboud
Nijmegen , , Netherlands

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Estimated Enrollment:

409

Study ID:

NCT00879944

Recruitment Status:

Completed

Sponsor:


Northwestern University

How clear is this clinincal trial information?

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