Psoriasis Clinical Trial

Treatment Effectiveness Among Psoriasis Patients Treated With Cosentyx (Secukinumab)

Summary

This was a retrospective cohort study utilizing data from Modernizing Medicine Data Services' (MMDS) electronic medical records (EMR)-based dermatology database to evaluate secukinumab patient characteristics, treatment patterns, and outcomes.

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Full Description

This was a retrospective cohort study utilizing data from Modernizing Medicine Data Services' (MMDS) electronic medical records (EMR)-based dermatology database to evaluate secukinumab patient characteristics, treatment patterns, and outcomes. Psoriasis (PsO) patients initiating secukinumab were identified and indexed to the first secukinumab use using the most recent data at study initiation (data period: March 1, 2018 to August 31, 2019) and with a subsequent data refresh (data period: March 1, 2017 - July 31, 2020).

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Eligibility Criteria

Inclusion Criteria:

≥1 orders/administrations for secukinumab within the index window (March 1, 2018 to August 31,2019 for the base analysis; March 1, 2018 to January 31, 2020 for the refresh analysis). The date of the first order or administration was be the index date
Patients in the MMDS database with a diagnosis of PsO on or prior to the 1st secukinumab order/administration
≥18 years of age as of the index date
To ensure capturing continuous patient activities in the EMR dataset, patients must have at least one more visit (any visit regardless of diagnosis) in addition to the index visit within the first 6 months after secukinumab initiation
Patients must have at least one visit (any visit regardless of diagnosis) within the 12 months pre-index period

Exclusion Criteria:

Evidence of secukinumab use in the 12-month pre-index period
Data quality issues (missing age, gender, prescription order information)

Study is for people with:

Psoriasis

Estimated Enrollment:

17743

Study ID:

NCT05320159

Recruitment Status:

Completed

Sponsor:

Novartis Pharmaceuticals

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There is 1 Location for this study

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Novartis Investigative Site
East Hanover New Jersey, 07936, United States

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Study is for people with:

Psoriasis

Estimated Enrollment:

17743

Study ID:

NCT05320159

Recruitment Status:

Completed

Sponsor:


Novartis Pharmaceuticals

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