Bladder Cancer Clinical Trial
Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary Cancer and Changes in Gut Microbiome
The objective of this pilot cohort study is to investigate associations between CIN and changes in gut microbiome composition profiles.
The long-term goal of this study is to alleviate the occurrence of CIN and to improve chemotherapy treatment outcomes. The identification of associations between CIN and chemotherapy-induced changes in gut microbiome composition profiles will increase our understanding of these mechanisms that underlie CIN. An increased understanding of the underlying mechanisms will provide targets for the development of novel interventions to help alleviate CIN.
at least 20 years of age
last chemotherapy more than 3 years ago
scheduled to receive moderate to highly emetogenic chemotherapy with or without targeted therapies including immunotherapies
concurrent radiation therapy
concurrent antibiotic treatment
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