The object of our research is to investigate the relative efficacy of liposomal bupivacaine administered via an Erector Spinae Plane (ESP) block as compared to our standard of care medication solution of (bupivacaine mixed with epinephrine, dexamethasone, and clonidine) for pain management in subjects undergoing bilateral surgical intervention for breast cancer. This will be an investigator-initiated, double-blind, patient-controlled, randomized control trial comparing pain scores at 48 hours after injection.
Adults 18 to 75 years of age at screening Scheduled to undergo oncoplastic bilateral mastectomy and reconstruction surgery at Tufts Medical Center
Exclusion Criteria:
Adults unable to consent (inability to read, write, or has some impairment that hampers consent process or documentation, or cognitively impaired adults) Pregnant women Pregnant minors Woman of childbearing potential who are unwilling or unable to complete a pregnancy test Minors i.e., individuals who are not yet adults (neonates, children, teenagers) Wards of the state Non-viable neonates Neonates of uncertain viability Prisoners Adults with known allergy, hypersensitivity, intolerance or contraindication to study medication