Colon Cancer Clinical Trial

A Study of the Possible Effects of Medication on Young Onset Colorectal Cancer (YOCRC)

Summary

This study will collect biospecimens (including blood, tissue, and stool samples) and health information to create a database-a type of collection of information-for better understanding young onset colorectal cancer (YOCRC). The study will include both people with YOCRC and healthy people.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

CRC Cohort:

18-49 years old
Histological or cytological diagnosis of colorectal adenocarcinoma
Planned CRC resection or biopsy of primary colon cancer (only patients providing tissue sample)
Enrollment in IRB# 20-315, Young Onset Gastrointestinal Cancer Prospective Registry (Andrea Cercek, PI)

Healthy Control Cohort:

18-49 years old
Scheduled for standard-of-care colonoscopy at MSK

Exclusion Criteria:

CRC Cohort:
Antibiotic use within 6 months of collection of stool for gut microbiome analysis
Known inherited cancer susceptibility gene
History of inflammatory bowel disease
Prior treatment for colorectal cancer Healthy Control Cohort:
History of or prior treatment for cancer ≤ 5 years prior to registration. Exceptions include non-melanoma skin cancer, ductal carcinoma in situ, bladder carcinoma in situ, or carcinoma-in-situ of the cervix.
Colonoscopy for indications of IBD and/or genetic predisposition (only patients providing tissue sample).

Study is for people with:

Colon Cancer

Estimated Enrollment:

160

Study ID:

NCT05568420

Recruitment Status:

Recruiting

Sponsor:

Memorial Sloan Kettering Cancer Center

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There is 1 Location for this study

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Memorial Sloan Kettering Cancer Center
New York New York, 10065, United States More Info
Andrea Cercek, MD
Contact
646-888-4189
David Kelsen, MD
Contact
646-888-4179

How clear is this clinincal trial information?

Study is for people with:

Colon Cancer

Estimated Enrollment:

160

Study ID:

NCT05568420

Recruitment Status:

Recruiting

Sponsor:


Memorial Sloan Kettering Cancer Center

How clear is this clinincal trial information?

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