Colon Cancer Clinical Trial
A Study of the Possible Effects of Medication on Young Onset Colorectal Cancer (YOCRC)
Summary
This study will collect biospecimens (including blood, tissue, and stool samples) and health information to create a database-a type of collection of information-for better understanding young onset colorectal cancer (YOCRC). The study will include both people with YOCRC and healthy people.
Eligibility Criteria
Inclusion Criteria:
CRC Cohort:
18-49 years old
Histological or cytological diagnosis of colorectal adenocarcinoma
Planned CRC resection biopsy, or colonoscopy ,including surveillance colonoscopies and/or have already undergone prior surgical resection, with tissue, including normal colonic mucosae distant from the malignant tumor (only patients providing tissue sample)
Enrollment in IRB# 20-315, Young Onset Gastrointestinal Cancer Prospective Registry (Andrea Cercek, PI)
Healthy Control Cohort:
18-49 years old
Scheduled for standard-of-care colonoscopy at MSK
Exclusion Criteria:
CRC Cohort:
Antibiotic use within 6 months of collection of stool for gut microbiome analysis s (only patients providing stool sample)
Known inherited cancer susceptibility gene
History of inflammatory bowel disease
Healthy Control Cohort:
Antibiotic use within 6 months of collection of stool for gut microbiome analysis (only patients providing stool sample)
History of or prior treatment for cancer ≤ 5 years prior to registration. Exceptions include non-melanoma skin cancer, ductal carcinoma in situ, bladder carcinoma in situ, or carcinoma-in-situ of the cervix.
Colonoscopy for indications of IBD, anemia and/or genetic predisposition (only patients providing tissue sample).
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There is 1 Location for this study
How clear is this clinincal trial information?