Colon Cancer Clinical Trial
Colonoscopy Using Nitrous Oxide- A Pilot Study in the USA
Summary
Colon cancer is the second most common cancer in men and the third most common cancer in women worldwide. The clinical objectives of administering sedation for GI endoscopy are to relieve patient anxiety and discomfort and to improve the outcome of the examination. Use of N2O could potentially provide an alternate safe and cheap option for patients who do not prefer IV sedation for colonoscopy
Full Description
Patients who are considered low risk for anesthesia administration (ASA class
Eligibility Criteria
Inclusion Criteria:
Men and women, more than 18 years old Scheduled for a colonoscopy at the Endoscopy unit
Exclusion Criteria:
High ASA risk (IV/ >)
History of chronic pain
Allergy to N2O or opioid or BDZ
No consent
Recent head injury with impairment of consciousness or Intracranial / Middle Ear surgery within the previous 6 months with or without residual deficits.
Pneumothorax, air embolism
Decompression sickness or within 48 hours of an underwater dive
Severe emphysema with bullae
Gross abdominal distension with suspicion for bowel obstruction
Intoxication
Maxillofacial injuries (where patient unable to administer the drug using a mouthpiece/mask, or there is the risk of causing further damage to facial wounds and there may also be a significant risk of blood inhalation)
Patients with chronic pulmonary disease for whom an inspired oxygen concentration of more than 28% oxygen might be dangerous
Patients on Methotrexate
Where patients need assistance to hold the mask or mouthpiece.
Retinal surgery within the last three months
Any patient who does not otherwise clinically qualify for standard sedation methods (i.e., those who require general anesthesia)
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There is 1 Location for this study
Little Rock Arkansas, 72205, United States
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