Colon Cancer Clinical Trial

Step Down Colon Cancer Risk

Summary

Hypothesis 1: Exercise will decrease serum markers in a dose response manner.

Hypothesis 2: Participants in the 60 minute intervention will have significantly higher physical activity levels than those in the 30 minute intervention at three months.

View Full Description

Full Description

Primary Aim: To conduct a dose response pilot trial of low (30 min/day) or high (60 min/day) dose exercise in men and women at increased risk of colon cancer. The major outcomes are changes in serum levels of four risk-related biomarkers: insulin, C-peptide, IL-6 and PGE-2.

Secondary Aim. To compare changes in the secondary outcome of physical activity over three months.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

aged 50 to 80
no personal cancer history
found to have an adenomatous polyp upon colonoscopy at BJH/WUSM in the previous six months
no contraindications to beginning an exercise program
no previous diagnosis of familial polyposis syndromes
no previous diagnosis of ulcerative colitis or Crohn's disease;

Exclusion Criteria:

Participants who are regular NSAID users will be excluded as this may interfere with the measurement of inflammatory marker outcomes. Regular use is defined as taking 80mg or more per day of aspirin, ibuprofen, naproxen or other NSAID 5 or more days of the week.

Study is for people with:

Colon Cancer

Estimated Enrollment:

17

Study ID:

NCT01476631

Recruitment Status:

Terminated

Sponsor:

Washington University School of Medicine

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

Washington University School of Medicine
St. Louis Missouri, 63110, United States

How clear is this clinincal trial information?

Study is for people with:

Colon Cancer

Estimated Enrollment:

17

Study ID:

NCT01476631

Recruitment Status:

Terminated

Sponsor:


Washington University School of Medicine

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.

Please confirm you are a US based health care provider:

Yes, I am a health care Provider No, I am not a health care provider