Prostate Cancer Clinical Trial

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A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer

Summary

The purpose of this study is to find out the effects of exercise therapy on indicators of prostate cancer in people with low-risk prostate cancer who are on active surveillance. The exercise therapy in this study will be regular home-based walking sessions on a treadmill, and that therapy will be assigned by an exercise physiologist (a medical professional who studies how exercise affects the human body). Some participants in this study will have the assigned exercise therapy, and some participants will participate in their usual exercise routines. Researchers will compare how the assigned exercise therapy and the usual exercise routines affect indicators of prostate cancer in participants. This study will not provide treatment for prostate cancer.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Age ≥ 18
Men with histologically confirmed localized prostate cancer undergoing active surveillance.
Inactive, defined as not meeting the national exercise guidelines for cancer patients (<150 minutes/week of moderate or vigorous exercise)43 as assessed by remote activity and heart rate tracking for a 7-day period prior to study entry (general physical activity screening assessment via smart watch).
Screening clearance by an MSK Exercise Physiologist (i.e., review of ECG and PAR-Q)
BMI <40 kg/m^2

Exclusion Criteria:

Enrollment in any other program that may alter the impact of exercise on tumor outcomes (e.g., weight loss program)
Any neoadjuvant anticancer treatment of any kind for prostate cancer in the last 5 years
Any history of systemic anticancer therapy in the last 15 years
Distant metastatic malignancy of any kind
Any other condition or intercurrent illness that, in the opinion of the investigator, makes the subject a poor candidate for study participation

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There are 8 Locations for this study

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University of California, Los Angeles (Data and Specimen Analysis Only)
Los Angeles California, 90095, United States More Info

Paul Boutros, PhD
Contact
310-794-7160

Jaron Arbet, PhD
Contact

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge New Jersey, 07920, United States More Info