Hypo-fractionated Stereotactic Body Radiotherapy for Localized Prostate Cancer

Inclusion Criteria:

Eligible patients will have clinical stage T1c, T2a, or T2b, a pre-biopsy PSA level <10 ng/mL and a biopsy Gleason score of 3+3 (or 3+4 if fewer than 30% of biopsy cores are involved).
The ability to understand and willingness to sign a written informed consent are necessary.

Exclusion Criteria:

Patients with tumor parameters that fall outside of the inclusion criteria.
Patients with evidence on imagining (bone scan, CT, or MRI) suggestive of disseminated disease.
Patients who have had any form of prior prostate treatment (surgery, radiotherapy, cryotherapy, high intensity focused ultrasound, TURP).
A prior course of hormone therapy (androgen deprivation) of greater than 3 months duration.
The use of other concurrent investigational agents.
There are no exclusions due to co-morbid disease or illnesses except for patients with severe inflammatory bowel disease.
No life expectancy restrictions will apply.
Performance status will not be considered.