Breast Cancer Clinical Trial

Clinical Trial Finder Breast Cancer Trials

Clinical Implementation of a Polygenic Risk Score (PRS) for Breast Cancer

See Locations Near You

Summary

This study aims to assess how a polygenic risk score (PRS) reported with the results of multi-gene panel testing affects the breast cancer risk management recommendations healthcare providers make to their patients. The PRS is a score based on small genetic changes, clinical history, and family history. The PRS is used to estimate remaining lifetime risk of developing breast cancer for patients with no personal history of breast cancer and an overall negative result from MGPT.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Female, age ≥ 18 years
Willing and able to provide meaningful informed consent
Willing and able to complete study procedures as described in this protocol
Electing to undergo multi-gene panel testing for hereditary breast cancer for clinical purposes at the time of consent
No personal history of cancer (except non-melanoma skin cancer) and meets NCCN guidelines for BRCA1/2 testing based on family history of breast and/or ovarian cancer
Meets Ambry criteria for clinical reporting of PRS score

Exclusion Criteria:

Prior germline BRCA1/2 testing
Not willing to receive PRS
Personal history of cancer, except non-melanoma skin cancer
Personal history of allogenic bone marrow/stem cell transplant

Study is for people with:

Breast Cancer

Estimated Enrollment:

118

Study ID:

NCT03688204

Recruitment Status:

Completed

Sponsor:

Ambry Genetics

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There are 3 Locations for this study

See Locations Near You

Providence Roy and Patricia Disney Family Cancer Center
Burbank California, 91505, United States
St Joseph Hospital of Orange
Orange California, 92868, United States
Edwards Comprehensive Cancer Center
Huntington West Virginia, 25701, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

118

Study ID:

NCT03688204

Recruitment Status:

Completed

Sponsor:


Ambry Genetics

How clear is this clinincal trial information?

Clinical Trial Resources

SurvivorNet’s Guide To Clinical Trials: What Are They And Are They Right for You?
Clinical Trials for Breast Cancer
Have You Been Diagnosed With Late-Stage Breast Cancer? Know That You Have Treatment Options.
×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.

Please confirm you are a US based health care provider:

Yes, I am a health care Provider No, I am not a health care provider