Breast Cancer Clinical Trial

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Examining the Long-Term Risks of Oophorectomy

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Summary

At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.

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Full Description

We are conducting a prospective, observational study of 32,175 women participants of the Nurse's Health Study who had a hysterectomy with or without removal of both ovaries. We are evaluating mortality and morbidity due to the following conditions: coronary heart disease, stroke, breast cancer, ovarian cancer, other cancer, hip fracture and death from all causes.

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Eligibility Criteria

Inclusion Criteria:

Women who had hysterectomies were classified into simple hysterectomy or hysterectomy with both ovaries removed.

Exclusion Criteria:

Evidence of cancer, coronary heart disease (MI or Angina Pectoris), stroke, or hip fracture before entering the study were excluded. Cancer as an indication for hysterectomy also excluded.
Women reporting unilateral oophorectomy, unknown oophorectomy status, unknown age of hysterectomy, or those who had oophorectomy before hysterectomy were excluded.

Study is for people with:

Breast Cancer

Estimated Enrollment:

32175

Study ID:

NCT00655447

Recruitment Status:

Completed

Sponsor:

Parker, William H., M.D.

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There is 1 Location for this study

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Parker, Rosenman, Rodi Gynecology Group
Santa Monica California, 90401, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

32175

Study ID:

NCT00655447

Recruitment Status:

Completed

Sponsor:


Parker, William H., M.D.

How clear is this clinincal trial information?

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