Breast Cancer Clinical Trial

Nutrition-Related Biomarkers in Predicting Breast Cancer Risk in Women

Summary

RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about nutrition-related changes that identify biomarkers related to cancer. It may also help doctors predict a woman's risk of developing breast cancer.

PURPOSE: This laboratory study is looking at nutrition-related biomarkers in predicting breast cancer risk in women.

View Full Description

Full Description

OBJECTIVES:

To complete characterization of metabolic serotypes based on the metabolome, and to adapt these profiles for human epidemiological studies.
To determine the extent to which metabolic profiles that are reflective of or independent of long-term caloric intake predict breast cancer risk in nested case-control studies.
To identify critical serum metabolites.

OUTLINE: Laboratory studies, including metabolome profiling by high performance liquid chromatography; and small molecule identification by mass spectroscopy, are performed on previously collected blood samples.

View Eligibility Criteria

Eligibility Criteria

DISEASE CHARACTERISTICS:

Meets 1 of the following criteria:

Confirmed breast cancer that was diagnosed at least 2 years after blood sample collection (case)

No prior diagnosis of cancer
Healthy participant (control)
Enrolled in the Nurses' Health Study
Banked blood samples available
Hormone receptor status not specified

PATIENT CHARACTERISTICS:

Menopausal status not specified

PRIOR CONCURRENT THERAPY:

Not specified

Study is for people with:

Breast Cancer

Estimated Enrollment:

1500

Study ID:

NCT00900367

Recruitment Status:

Active, not recruiting

Sponsor:

Brigham and Women's Hospital

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

Dana-Farber/Brigham and Women's Cancer Center
Boston Massachusetts, 02115, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

1500

Study ID:

NCT00900367

Recruitment Status:

Active, not recruiting

Sponsor:


Brigham and Women's Hospital

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.

Please confirm you are a US based health care provider:

Yes, I am a health care Provider No, I am not a health care provider