Heart Failure Clinical Trial

Clinical Trial Finder Heart Failure Trials

Evaluation of Vepoloxamer in Chronic Heart Failure

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Summary

The purpose of this study is to evaluate whether vepoloxamer can provide a blood chemical marker and functional benefit to damaged heart muscle cells. This will be evaluated by measurement of blood-based laboratory markers, exercise tolerance, and echocardiograms. In addition, the safety and blood levels of vepoloxamer in subjects with chronic heart failure will be evaluated.

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Eligibility Criteria

Inclusion Criteria:

Age 18 through 74
Duration of documented heart failure >3 months
On stable concomitant medication regimen ≥4 weeks
Left ventricular ejection fraction ≤35%
Systolic blood pressure ≥90 mmHg

Exclusion Criteria:

Severe valvular stenosis or primary valvular regurgitation as the cause of heart failure
History of myocardial infarction, coronary artery bypass graft surgery, or percutaneous intervention within the prior 3 months
Estimated glomerular filtration rate ≤45 mL/min/1.73 m2
Acutely decompensated heart failure within 1 month prior to the screening visit

Study is for people with:

Heart Failure

Phase:

Phase 2

Estimated Enrollment:

10

Study ID:

NCT02596477

Recruitment Status:

Terminated

Sponsor:

Mast Therapeutics, Inc.

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There are 3 Locations for this study

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Research Center
Detroit Michigan, 48202, United States
Research Center
Tupelo Mississippi, 38801, United States
Research Center
Cardiff New South Wales, 2285, Australia
Research Center
Melbourne Victoria, , Australia

How clear is this clinincal trial information?

Study is for people with:

Heart Failure

Phase:

Phase 2

Estimated Enrollment:

10

Study ID:

NCT02596477

Recruitment Status:

Terminated

Sponsor:


Mast Therapeutics, Inc.

How clear is this clinincal trial information?

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