Kidney Cancer Clinical Trial

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Disease Burden and Biology Using Tumor Cell Free DNA in Metastatic Kidney Cancer

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Summary

This study will assess whether DNA released by kidney cancer into the blood stream and urine of patients can be used to monitor tumor burden and tumor response to treatment in patients receiving immunotherapy

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Full Description

Primary Objective:

- Evaluate tumor cell free (cf)DNA as a dynamic marker of response to immuno-oncology (IO) therapy

Exploratory Objective:

- Collect data on somatic mutations in cfDNA to gain insight into the biology of IO-responders and -non-responders

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Renal Cell Carcinoma with clear cell component
Stage IV
Receiving IO-containing regimen
Measurable disease per RECIST 1.1

Exclusion Criteria:

Active cancer (exclusion criteria only for healthy patient cohort)

Study is for people with:

Kidney Cancer

Estimated Enrollment:

150

Study ID:

NCT04883827

Recruitment Status:

Recruiting

Sponsor:

Vanderbilt-Ingram Cancer Center

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There are 3 Locations for this study

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Tennessee Valley Health Care System
Nashville Tennessee, 37212, United States More Info
Scott Haake, MD
Contact
615-936-8422
[email protected]
Scott Haake, MD
Principal Investigator
Vanderbilt University Medical Center
Nashville Tennessee, 37232, United States More Info
Scott Haake, MD
Contact
615-936-8422
[email protected]
Vanderbilt-Ingram Service for Timely Access
Contact
800-811-8480
[email protected]
Scott Haake, MD
Principal Investigator
The University of Texas MD Anderson Cancer Center
Houston Texas, 77030, United States More Info
Eric Jonasch, MD
Contact
[email protected]
Eric Jonasch, MD
Principal Investigator

How clear is this clinincal trial information?

Study is for people with:

Kidney Cancer

Estimated Enrollment:

150

Study ID:

NCT04883827

Recruitment Status:

Recruiting

Sponsor:


Vanderbilt-Ingram Cancer Center

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