Lung Cancer Clinical Trial
Study to Compare AMG 510 “Proposed INN Sotorasib” With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200).
Summary
A Phase 3 Study to Compare AMG 510 with Docetaxel in Non Small Cell Lung Cancer (NSCLC) subjects with KRAS p. G12c mutation
Eligibility Criteria
Inclusion Criteria:
Men or women greater than or equal to 18 years old.
ECOG ≤ 1
Pathologically documented, previously treated, locally-advanced and unresectable or metastatic NSCLC with KRAS p.G12C mutation confirmed through central testing or have documentation of KRAS p.G12C mutation through Amgen Study 20190294 prior to enrollment
Exclusion Criteria:
Active brain metastases
Myocardial infarction within 6 months of study day 1
Gastrointestinal (GI) tract disease causing the inability to take oral medication
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There are 269 Locations for this study
Anaheim California, 92801, United States
Duarte California, 91010, United States
Long Beach California, 90813, United States
Los Angeles California, 90095, United States
Los Angeles California, 90095, United States
Sacramento California, 95817, United States
Santa Barbara California, 93105, United States
Stanford California, 94305, United States
Torrance California, 90502, United States
Denver Colorado, 80218, United States
Norwalk Connecticut, 06856, United States
Newark Delaware, 19713, United States
Washington District of Columbia, 20010, United States
Fort Myers Florida, 33901, United States
Hollywood Florida, 33021, United States
Saint Petersburg Florida, 33705, United States
Tallahassee Florida, 32308, United States
Atlanta Georgia, 30332, United States
Atlanta Georgia, 30341, United States
North Chicago Illinois, 60064, United States
Fort Wayne Indiana, 46804, United States
Shreveport Louisiana, 71103, United States
Clinton Maryland, 20735, United States
Lowell Massachusetts, 01854, United States
Ann Arbor Michigan, 48109, United States
Grand Rapids Michigan, 49503, United States
Minneapolis Minnesota, 55404, United States
Kansas City Missouri, 64132, United States
Las Vegas Nevada, 89169, United States
Florham Park New Jersey, 07932, United States
Albany New York, 12208, United States
Albany New York, 12208, United States
Bronx New York, 10461, United States
Bronx New York, 10468, United States
Lake Success New York, 11042, United States
Winston-Salem North Carolina, 27157, United States
Cincinnati Ohio, 45219, United States
Portland Oregon, 97227, United States
Charleston South Carolina, 29414, United States
Greenville South Carolina, 29607, United States
Chattanooga Tennessee, 37404, United States
Knoxville Tennessee, 37909, United States
Nashville Tennessee, 37203, United States
Bedford Texas, 76022, United States
Dallas Texas, 75246, United States
Dallas Texas, 75390, United States
Fort Worth Texas, 76104, United States
Harlingen Texas, 78550, United States
Houston Texas, 77030, United States
Irving Texas, 75063, United States
Tyler Texas, 75701, United States
Murray Utah, 84107, United States
Fairfax Virginia, 22031, United States
Norfolk Virginia, 23502, United States
Blacktown New South Wales, 2148, Australia
Camperdown New South Wales, 2050, Australia
Kogarah New South Wales, 2217, Australia
Liverpool New South Wales, 2170, Australia
Chermside Queensland, 4032, Australia
Woolloongabba Queensland, 4102, Australia
Woodville South South Australia, 5011, Australia
Clayton Victoria, 3168, Australia
Melbourne Victoria, 3000, Australia
Subiaco Western Australia, 6008, Australia
Brussels , 1000, Belgium
Bruxelles , 1200, Belgium
Charleroi , 6000, Belgium
Edegem , 2650, Belgium
Gent , 9000, Belgium
Leuven , 3000, Belgium
Liege , 4000, Belgium
Roeselare , 8800, Belgium
Sint-Niklaas , 9100, Belgium
Ijui Rio Grande Do Sul, 98700, Brazil
Porto Alegre Rio Grande Do Sul, 90610, Brazil
Sao Paulo São Paulo, 01308, Brazil
Sao Paulo São Paulo, 01321, Brazil
Sao Paulo São Paulo, 04501, Brazil
Sao Paulo São Paulo, 05652, Brazil
São José Do Rio Preto São Paulo, 15090, Brazil
Rio de Janeiro , 22250, Brazil
Rio de Janeiro , 22793, Brazil
São Paulo , 01509, Brazil
Calgary Alberta, T2N 4, Canada
Edmonton Alberta, T6G 1, Canada
Hamilton Ontario, L8V 5, Canada
London Ontario, N6A 5, Canada
Ottawa Ontario, K1H 8, Canada
Toronto Ontario, M5G 2, Canada
Montreal Quebec, H2X 3, Canada
Herlev , 2730, Denmark
København , 2100, Denmark
Odense C , 5000, Denmark
Helsinki , 00180, Finland
Helsinki , 00290, Finland
Oulu , 90220, Finland
Turku , 20520, Finland
Brest , 29609, France
Créteil , 94010, France
Grenoble , 38700, France
Lille Cedex , 59037, France
Limoges Cedex , 87042, France
Lyon , 69008, France
Marseille Cedex 20 , 13915, France
Paris Cedex 20 , 75020, France
Paris , 75005, France
Paris , 75014, France
Paris , 75018, France
Pessac Cedex , 33604, France
Pierre-Benite cedex , 69495, France
Rennes , 35033, France
Saint Herblain , 44800, France
Strasbourg cedex , 67091, France
Toulouse Cedex 9 , 31059, France
Villejuif , 94805, France
Berlin , 13125, Germany
Berlin , 13353, Germany
Dresden , 01307, Germany
Essen , 45147, Germany
Esslingen am Neckar , 73730, Germany
Frankfurt am Main , 60590, Germany
Gauting , 82130, Germany
Grosshansdorf , 22927, Germany
Hamburg , 20251, Germany
Heidelberg , 69126, Germany
Immenstadt , 87509, Germany
Köln , 50937, Germany
Leipzig , 04357, Germany
Moers , 47441, Germany
Oldenburg , 26121, Germany
Athens , 115 2, Greece
Athens , 11526, Greece
Athens , 11527, Greece
Athens , 14564, Greece
Athens , 18547, Greece
Heraklion - Crete , 71110, Greece
Larissa , 41110, Greece
Patra , 26504, Greece
Thessaloniki , 54007, Greece
Thessaloniki , 54622, Greece
Thessaloniki , 54645, Greece
Thessaloniki , 55236, Greece
Budapest , 1083, Hungary
Budapest , 1121, Hungary
Farkasgyepu , 8582, Hungary
Gyula , 5700, Hungary
Kaposvar , 7400, Hungary
Miskolc , 3529, Hungary
Szekesfehervar , 8000, Hungary
Tatabanya , 2800, Hungary
Torokbalint , 2045, Hungary
Avellino , 83100, Italy
Bari , 70124, Italy
Bologna , 40138, Italy
Catania , 95123, Italy
Firenze , 50134, Italy
Milano , 20122, Italy
Milano , 20132, Italy
Milano , 20133, Italy
Monserrato CA , 09042, Italy
Monza (MB) , 20900, Italy
Napoli , 80131, Italy
Orbassano (TO) , 10043, Italy
Padova , 35128, Italy
Ravenna , 48100, Italy
Roma , 00161, Italy
Roma , 00168, Italy
Nagoya-shi Aichi, 464-8, Japan
Nagoya-shi Aichi, 466-8, Japan
Chiba-shi Chiba, 260-8, Japan
Kashiwa-shi Chiba, 277-8, Japan
Matsuyama-shi Ehime, 791-0, Japan
Fukuoka-shi Fukuoka, 811-1, Japan
Fukuoka-shi Fukuoka, 812-8, Japan
Kitakyushu-shi Fukuoka, 807-8, Japan
Fukuyama-shi Hiroshima, 720-0, Japan
Hiroshima-shi Hiroshima, 734-8, Japan
Sapporo-shi Hokkaido, 003-0, Japan
Akashi-shi Hyogo, 673-8, Japan
Himeji-shi Hyogo, 670-8, Japan
Itami-shi Hyogo, 664-8, Japan
Kobe-shi Hyogo, 650-0, Japan
Kanazawa-shi Ishikawa, 920-8, Japan
Kawasaki-shi Kanagawa, 216-8, Japan
Sagamihara-shi Kanagawa, 252-0, Japan
Yokohama-shi Kanagawa, 241-8, Japan
Kyoto-shi Kyoto, 606-8, Japan
Natori-shi Miyagi, 981-1, Japan
Sendai-shi Miyagi, 980-0, Japan
Niigata-shi Niigata, 951-8, Japan
Okayama-shi Okayama, 700-8, Japan
Habikino-shi Osaka, 583-8, Japan
Hirakata-shi Osaka, 573-1, Japan
Osaka-shi Osaka, 534-0, Japan
Osaka-shi Osaka, 541-8, Japan
Osakasayama-shi Osaka, 589-8, Japan
Sakai-shi Osaka, 591-8, Japan
Saga-shi Saga, 840-8, Japan
Kitaadachi-gun Saitama, 362-0, Japan
Otsu-shi Shiga, 520-2, Japan
Bunkyo-ku Tokyo, 113-8, Japan
Chuo-ku Tokyo, 104-0, Japan
Koto-ku Tokyo, 135-8, Japan
Yonago-shi Tottori, 683-8, Japan
Wakayama-shi Wakayama, 641-8, Japan
Iwakuni-shi Yamaguchi, 740-8, Japan
Ube-shi Yamaguchi, 755-0, Japan
Cheongju-si, Chungcheongbuk-do , 28644, Korea, Republic of
Goyang-si Gyeonggi-do , 10408, Korea, Republic of
Seongnam-si, Gyeonggi-do , 13496, Korea, Republic of
Seongnam-si, Gyeonggi-do , 13620, Korea, Republic of
Seoul , 03080, Korea, Republic of
Seoul , 03181, Korea, Republic of
Seoul , 03722, Korea, Republic of
Seoul , 05505, Korea, Republic of
Seoul , 06351, Korea, Republic of
Seoul , 06591, Korea, Republic of
Ulsan , 44033, Korea, Republic of
Amsterdam , 1066 , Netherlands
Groningen , 9713 , Netherlands
Nijmegen , 6525 , Netherlands
Rotterdam , 3015 , Netherlands
Utrecht , 3584 , Netherlands
Gdansk , 80-21, Poland
Lublin , 20-60, Poland
Poznan , 60-56, Poland
Warszawa , 02-78, Poland
Wroclaw , 53-41, Poland
Lisboa , 1769-, Portugal
Matosinhos , 4464-, Portugal
Porto , 4099-, Portugal
Porto , 4200-, Portugal
Porto , 4200-, Portugal
Moscow , 12528, Russian Federation
Nizhniy Novgorod , 60308, Russian Federation
Omsk , 64401, Russian Federation
Saint-Petersburg , 19775, Russian Federation
Saint-Petersburg , 19775, Russian Federation
Malaga AndalucÃ-a, 29011, Spain
Las Palmas de Gran Canaria Canarias, 35016, Spain
Barcelona Cataluña, 08035, Spain
Barcelona Cataluña, 08036, Spain
Barcelona Cataluña, 08041, Spain
Hospitalet de Llobregat Cataluña, 08907, Spain
Valencia Comunidad Valenciana, 46010, Spain
A Coruña Galicia, 15006, Spain
Majadahonda Madrid, 28222, Spain
Madrid , 28034, Spain
Madrid , 28041, Spain
Madrid , 28046, Spain
Gavle , 801 8, Sweden
Goteborg , 413 4, Sweden
Linkoping , 581 8, Sweden
Lund , 221 8, Sweden
Stockholm , 171 6, Sweden
Umea , 901 8, Sweden
Basel , 4031, Switzerland
Bern , 3010, Switzerland
Geneve , 1205, Switzerland
Lausanne , 1011, Switzerland
Winterthur , 8401, Switzerland
Zurich , 8091, Switzerland
Taichung , 40447, Taiwan
Taichung , 40705, Taiwan
Tainan , 70403, Taiwan
Taipei , 10002, Taiwan
Cambridge , CB2 0, United Kingdom
Edinburgh , EH4 2, United Kingdom
London , SW3 6, United Kingdom
London , W1G 6, United Kingdom
Manchester , M20 4, United Kingdom
Nottingham , NG5 1, United Kingdom
Oxford , OX3 7, United Kingdom
Sutton , SM2 5, United Kingdom
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