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Cytogenetic Study of Ocular Melanoma Summary Patients who are diagnosed with choroidal melanoma and undergo I-125 plaque or enucleation surgery consent to participate in the study. A tumor sample taken during surgery is studied in the lab for genetic features. These features and features of subjects' clinical course are recorded. Analysis of the data may identify genetic features that are indicative of prognostic factors including risk of metastasis.
View Full Description Full Description The Jules Stein Eye Institute Ocular Melanoma Research Group is conducting cytogenetic studies of choroidal melanoma to improve the screening of biopsy samples of choroidal melanoma through cytogenetic analysis. Our goal is to identify molecular probes that specifically target regions of chromosomes that undergo changes characteristic of metastatic choroidal melanoma.
View Eligibility Criteria Eligibility Criteria Inclusion Criteria: Patient with diagnosis of ocular melanoma Patient with local treatment plan for ocular melanoma- plaque brachytherapy or enucleation Patient 18 years of age or older Archival enucleation specimens with diagnosis of ocular melanoma Exclusion Criteria: Patient who refuses local melanoma treatment Patient who refuses to participate in this study
Check Your Eligibility
Let’s see if you might be eligible for this study.
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There is 1 Location for this study
Jules Stein Eye Institute Los Angeles California, 90095, United States
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