Psoriasis Clinical Trial

A Study Evaluating the Efficacy and Tolerability of Enstilar Foam in Patients With Nail Psoriasis

Summary

The aim of the proposed study is to evaluate the efficacy and safety of Enstilar Foam (calcipotriene and betamethasone dipropionate) for the treatment of nail psoriasis.

View Full Description

Full Description

Eligible subjects will be provided twice daily. Enstilar Foam (calcipotriene and betamethasone dipropionate). Subjects will be instructed to apply a thin layer on the nail plate, around the nail plate and under the nail plate. The patient will be instructed to apply one application at night immediately before bed and not wash their hands before morning. All subjects who completed the 6-month treatment will be followed for 1 month after discontinuation.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Must have a diagnosis of nail psoriasis in fingernail or toenails
History of plaque psoriasis or psoriatic arthritis
Target nail will be KOH negative for dermatophyte fungus
Must give written informed consent prior to study procedures being conducted, also give consent to the release and use of protected health information (PHI)
Between the ages of 18 and 85 years old
Candidate for topical therapy in the opinion of the investigator

Exclusion Criteria:

Males and Females unable to practice effective contraception throughout the study
Unable to comply with the protocol
Nursing mothers, pregnant women, and women planning to become pregnant while in this study
Patients with erythrodermic or pustular psoriasis
Sustained treatment to target fingernail within 6 months prior to screening
History of trauma or surgery to target fingernail
History of disease known to affect nails such as lichen planus, onychomycosis
History of systemic psoriasis therapy for less than 6 months

Study is for people with:

Psoriasis

Phase:

Phase 4

Estimated Enrollment:

3

Study ID:

NCT04227288

Recruitment Status:

Completed

Sponsor:

University of Alabama at Birmingham

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

The University of Alabama at Birmingham
Birmingham Alabama, 35233, United States

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Phase 4

Estimated Enrollment:

3

Study ID:

NCT04227288

Recruitment Status:

Completed

Sponsor:


University of Alabama at Birmingham

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.