Psoriasis Clinical Trial
A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)
Summary
The purpose of the study is to evaluate how effective JNJ-77242113 is in participants with moderate to severe plaque psoriasis compared to placebo and deucravacitinib.
Eligibility Criteria
Inclusion Criteria:
Diagnosis of plaque psoriasis, with or without psoriatic arthritis (PsA), for at least 26 weeks prior to the first administration of study intervention
Total body surface area (BSA) greater than or equal to (>=)10 percent (%) at screening and baseline
Total psoriasis area and severity index (PASI) >=12 at screening and baseline
Total investigator global assessment (IGA) >=3 at screening and baseline
Candidate for phototherapy or systemic treatment for plaque psoriasis
Exclusion Criteria:
Nonplaque form of psoriasis (for example, erythrodermic, guttate, or pustular)
Current drug-induced psoriasis (for example, a new onset of psoriasis or an exacerbation of psoriasis from beta blockers, calcium channel blockers, or lithium)
A current diagnosis or signs or symptoms of severe, progressive, or uncontrolled renal, liver, cardiac, vascular, pulmonary, gastrointestinal, endocrine, neurologic, hematologic, rheumatologic, psychiatric, or metabolic disturbances
Known allergies, hypersensitivity, or intolerance to JNJ-77242113, deucravacitinib or to any of the excipients or components of the study intervention
Major surgical procedure, (for example, requiring general anesthesia) within 8 weeks before screening, or will not have fully recovered from surgical procedure, or has a surgical procedure planned during the time the participant is expected to participate in the study
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There are 123 Locations for this study
Phoenix Arizona, 85032, United States
Encinitas California, 92024, United States
Encino California, 91436, United States
Los Angeles California, 90024, United States
Los Angeles California, 90056, United States
Oceanside California, 92056, United States
Miami Florida, 33155, United States
Miami Florida, 33173, United States
Tampa Florida, 33613, United States
Douglasville Georgia, 30135, United States
Rolling Meadows Illinois, 60008, United States
Louisville Kentucky, 40217, United States
Owensboro Kentucky, 42301, United States
Rockville Maryland, 20850, United States
Brighton Massachusetts, 02135, United States
Methuen Massachusetts, 01844, United States
Bay City Michigan, 48706, United States
Caledonia Michigan, 49316, United States
Canton Michigan, 48187, United States
Troy Michigan, 48084, United States
Kirksville Missouri, 63501, United States
Bexley Ohio, 43209, United States
Tulsa Oklahoma, 74137, United States
Portland Oregon, 97210, United States
Philadelphia Pennsylvania, 19103, United States
Charleston South Carolina, 29407, United States
Greenville South Carolina, 29615, United States
Arlington Texas, 76011, United States
Dallas Texas, 75390, United States
San Antonio Texas, 78229, United States
Webster Texas, 77598, United States
Bountiful Utah, 84010, United States
Springville Utah, 84663, United States
West Valley City Utah, 84120, United States
Norfolk Virginia, 23502, United States
Benowa , 4217, Australia
Kogarah , 2217, Australia
Melbourne , 3004, Australia
Mitcham , 3132, Australia
Parkville , 3050, Australia
Botucatu , 18618, Brazil
Brasilia , 72.14, Brazil
Ribeirao Preto , 14048, Brazil
Santo Andre , 09060, Brazil
Sao Paulo , 05403, Brazil
Surrey British Columbia, V3R 6, Canada
Winnipeg Manitoba, R3M 3, Canada
London Ontario, N6A 5, Canada
Markham Ontario, L3P 1, Canada
Mississauga Ontario, L4Y 4, Canada
Peterborough Ontario, K9J 5, Canada
Toronto Ontario, M2N 3, Canada
Toronto Ontario, M3H 5, Canada
Windsor Ontario, N8T 1, Canada
Montreal Quebec, H2X 2, Canada
Quebec , G1V 4, Canada
Augsburg , 86150, Germany
Bad Bentheim , 48455, Germany
Berlin , 13627, Germany
Bochum , 44793, Germany
Darmstadt , 64283, Germany
Dresden , 01307, Germany
Dulmen , 48249, Germany
Dusseldorf , 40212, Germany
Friedrichshafen , 88045, Germany
Hamburg , 20095, Germany
Heidelberg , 69120, Germany
Mahlow , 15831, Germany
Mainz , 55131, Germany
Merzig , 66663, Germany
Muenster , 48149, Germany
Oldenburg , 26133, Germany
Witten , 58453, Germany
Wuppertal , 42287, Germany
Budapest , 1152, Hungary
Gyongyos , 3200, Hungary
Gyula , 5700, Hungary
Kecskemet , 6000, Hungary
Zalaegerszeg , H-890, Hungary
Ansan-si , 15355, Korea, Republic of
Anyang-si , 14068, Korea, Republic of
Bucheon si , 14647, Korea, Republic of
Gwangju , 61453, Korea, Republic of
Seongnam , 13496, Korea, Republic of
Seoul , 05505, Korea, Republic of
Seoul , 8308, Korea, Republic of
Bialystok , 15 79, Poland
Katowice , 40-56, Poland
Katowice , 40-61, Poland
Kielce , 25-31, Poland
Krakow , 30-00, Poland
Krakow , 30-30, Poland
Krakow , 30-34, Poland
Krakow , 31-55, Poland
Olsztyn , 10 11, Poland
Warsaw , 02-96, Poland
Warszawa , 02 67, Poland
Warszawa , 02-66, Poland
Wrocław , 51-68, Poland
Cluj-Napoca , 40010, Romania
Craiova , 20054, Romania
Craiova , 20064, Romania
Iasi , 70038, Romania
Oradea , 41016, Romania
Timisoara , 30075, Romania
Alcorcon , 28922, Spain
Badalona , 08916, Spain
Barcelona , 08036, Spain
Manises , 46940, Spain
Salamanca , 37007, Spain
Santiago de Compostela , 15702, Spain
Santiago de Compostela , 15706, Spain
Sevilla , 41009, Spain
Sevilla , 41014, Spain
Villajoyosa , 03570, Spain
Zaragoza , 50009, Spain
Kaohsiung , 80756, Taiwan
Kaohsiung , 81362, Taiwan
Taichung , 40201, Taiwan
Taichung , 40705, Taiwan
Tainan , 710, Taiwan
Taipei , 110, Taiwan
Taipei , 116, Taiwan
How clear is this clinincal trial information?

Please confirm you are a US based health care provider:
Yes, I am a health care Provider No, I am not a health care providerSign Up Now.
Take Control of Your Disease Journey.
Sign up now for expert patient guides, personalized treatment options, and cutting-edge insights that can help you push for the best care plan.