James Van Der Beek's Cancer Journey
- Actor James Van Der Beek, who has been battling stage 3 colorectal cancer since August 2023, is doing “better” after his most recent round of treatment for colon cancer, his former co-star Joshua Jackson said in a recent interview.
- Colon cancers start out as a polyp, or small growth, in the colon that causes no symptoms. Although polyps can’t be felt, they can be picked up by screening tests before they cause a problem. It takes up to 10 years for a colon polyp to become a full-blown cancer, which gives doctors time to remove the polyp before it causes a problem.
- The U.S. Preventive Services Task Force recommends state colon cancer screenings should begin at 45-years-old. This is in response to a rise in colon cancer diagnoses in younger adults. In the past, the disease had predominantly been found in adults 50-years or older, but for those predisposed to get it at a younger age, these new guidelines could potentially help catch it at an earlier stage.
Jackson, who rose to fame in his role as Pacey Witter on the WB series “Dawson’s Creek, alongside Van Der Beek, who played Dawson Leary, shared the health update during a recent episode of The Jennifer Hudson Show.
Read MoreView this post on Instagram
He continued, “Yeah, thoughts, prayers and just anything that can be done for him, and his family. He has a large, young family.”
Jackson also noted that the “whole gang” from “Dawson’s Creek” has gotten “back together” since Van Der Beek informed them of his cancer diagnosis, saying how they keeping trouble with a “little group text.”
In another interview from earlier this month, Jackson also spoke about Van Der Beek’s cancer journey on actor Jesse Tyler Ferguson’s podcast “Dinner’s On Me,” explaining, “James is going through something really, truly terrible right now.
“And, I wish I could take credit for this, but I was kind of the absentee partner here, but the girls all got together and were like, ‘We need to do something to help this guy out.'”
We’re delighted to hear how Jackson and Van Der Beek’s fellow former co-stars are sticking by his side throughout his journey, which he is also powering through with the support of his beloved wife Kimberly and their six children.
Van Der Beek, who was diagnosed just a few years after tragically losing his mother Melina at age 70.

Understanding Colon Cancer & Van Der Beek’s Diagnosis
James Van Der Beek learned he had colorectal cancer last year after getting a colonoscopy done. He told People in his tell-all interview that his bowel issues led him to get checked.
“I thought maybe I needed to stop coffee. Or maybe not put cream in the coffee. But when I cut that out and it didn’t improve, I thought, ‘All right, I better get this checked out,'” he said.
View this post on Instagram
Before Van Der Beek’s interview was published, the beloved actor wrote the following alongside a November 3rd Instagram post, “‘It is cancer…’ Each year, approximately 2 billion people around the world receive this diagnosis. And I’m one of them. There’s no playbook for how announce these things, but I’d planned on talking about it at length with People magazine at some point soon… to raise awareness and tell my story on my own terms. But that plan had to be altered early this morning when I was informed that a tabloid was going to run with the news.
“I’ve been dealing with this privately until now, getting treatment and dialing in my overall health with greater focus than ever before. I’m in a good place and feeling strong. It’s been quite the initiation, and I’ll tell you more when I’m ready.
“Apologies to all the people in my life who I’d planned on telling myself. Nothing about this process has occurred on my preferred timeline… But we roll with it, taking each surprise as a signpost, pointing us toward a greater destiny than we would have discovered without divine intervention,” he continued. “Please know that my family and I deeply appreciate all the love and support.”
View this post on Instagram
Colorectal cancer happens when polyps are not removed and become cancerous. It can take up to 10 years for a colon polyp to become cancerous, according to SurvivorNet experts.
“We know that colon cancers can be prevented when polyps are found early,” Dr. Heather Yeo, a surgical oncologist who specializes in colorectal cancers at Weill Cornell Medicine, told SurvivorNet.
“Lowering the screening age helps somewhat with this, but access to care is a real problem,” Dr. Yeo added.
Dr. Zuri Murrell, a colorectal cancer surgeon and Director of the Cedars-Sinai Colorectal Cancer Center, previously explained the colonoscopy procedure to SurvivorNet.
“When we see a polyp, we actually physically take the polyp out through the colonoscope,” he explained. “What does that mean? That means we basically put a wire through with a little bit of a flange at the end, and we pull the polyp out. Now, note there is no pain with that. Inside the colon, there are no pain fibers. So, there’s no pain.”
The advantage of a colonoscopy is that your doctor can remove any polyps found during the test. Many colon cancers can be caught on colonoscopy before they develop or when the polyps are small enough to be removed without surgery.
Looking for Polyps During Colonoscopy
The American Gastrointestinal Association lowered the recommended initial age for a colorectal screening from 50 to 45.
The U.S. Preventive Services Task Force recommends guidelines that state colon cancer screenings should begin at 45 years old. This is in response to the increase we see in colon cancer diagnoses in younger adults.
However, many insurance companies still do not cover the cost of screenings for those under 50. In the past, the disease had predominantly been found in adults 50 years or older, but for those predisposed to getting it at a younger age, these new guidelines could help catch it earlier.
Understanding Treatment Options
Although, Van Der Beek has chosen to keep the details of his colon cancer journey and treatment process private, it’s important to understand that your doctor has many ways to treat colon cancer, depending on what stage the cancer is, including:
- Surgery
- Radiation therapy
- Chemotherapy
- Targeted therapy
- Immunotherapy
Surgery
Surgery is the main treatment for most early-stage colon cancers, according to the doctors SurvivorNet spoke with. The surgeon will remove the part of the colon or rectum where there is cancer, along with a small area of healthy tissue around it. Taking out as much of the cancer as possible is important for improving your outcome.
The surgery may be performed through small incisions (laparoscopy), or through a larger incision. Some people may need to wear a special bag (ostomy) to collect wastes after surgery.
Deciding When to Operate on Colon Cancer
Radiation Therapy
This treatment aims high-energy x-rays at the cancer to destroy the abnormal cells. The radiation can come from a machine outside your body, or be placed directly inside your body. Sometimes people get radiation before surgery, to shrink the tumor and make it easier for the surgeon to remove. This is called neoadjuvant radiation.
Chemotherapy
This treatment uses strong medicine to stop cancer cells from dividing, no matter where they are in your body. You may get a combination of chemotherapy drugs as your first treatment. Chemotherapy has been very well studied for colorectal cancer, and it is known to improve survival.
The most common therapy is a combination of chemo drugs called FOLFOX:
- FOL = leucovorin calcium (folinic acid)
- F = fluorouracil
- OX = oxaliplatin
Your doctor may add medications like irinotecan (FOLFIRI) or cetuximab, depending on how well your tumor shrinks with treatment and other specifics about your particular cancer. For FOLFOX, the medications are given through the vein and require regular doctor visits.
To determine exactly which chemotherapy regimen you get, your doctor will consider your age and how well you might tolerate the side effects of chemotherapy. Gene mutations (for example, BRAF and KRAS) and the location of the primary colon tumor also factor into the decision.
You can also get chemotherapy before colon cancer surgery, which is called neoadjuvant chemotherapy. Getting chemo first helps to shrink the tumor, which can make both the surgery and recovery easier, according to SurvivorNet’s experts. Chemo is also a treatment for cancer that returns after therapy.
Targeted Therapy
This treatment targets substances like proteins or genes that the cancer needs to grow. This makes targeted therapy more precise than chemotherapy, and less likely to damage healthy cells. One example of targeted therapy is bevacizumab (Avastin), which stops the growth of new blood vessels that feed tumors. Another group of targeted therapies are called epidermal growth factor receptor (EGFR) inhibitors, which block the cancer from growing.
Immunotherapy
This treatment makes your own immune system a more efficient cancer fighter. A group of drugs called checkpoint inhibitors, which includes pembrolizumab (Keytruda) and nivolumab (Opdivo), work by preventing cancer cells from hiding from your immune system. Checkpoint inhibitors may extend the amount of time before the cancer spreads.
Dr. Paul Oberstein, on which treatments doctors use to turn stage 4 colon cancer into a chronic but manageable disease
Coping With a Diagnosis & The Power of Support
Coping with a diagnosis involves a range of emotions from anger to sadness and everything in between.
Sarah Stapleton, a licensed clinical social worker, encourages cancer warriors and their families to be “patient with your emotions.”
It’s also important that you understand how you communicate with your providers, but also with your loved ones,” Stapleton said. “We can’t always assume that people know what we need at a given time, and there are going to be times when you don’t want to speak about your diagnosis and you don’t want to speak about cancer.
Psychiatrist Dr. Lori Plutchik previously explained to SurvivorNet some tips for cancer warriors and their caregivers for managing emotions after a diagnosis. She emphasized getting extra support from loved ones.
“Some people don’t need to go outside of their family and friend circle. They feel like they have enough support there,” Dr. Plutchik said. “But for people who feel like they need a little bit more, it is important to reach out to a mental health professional.”
“Patients who have just been diagnosed with cancer sometimes wonder how they are going to handle the diagnosis of the cancer in social situations,” Dr. Plutchik added. “How much information they should share and with whom they should share the information, everybody is different.”
Ultimately it comes down to what feels right. Loved ones supporting a cancer warrior are encouraged to respect the wishes of the cancer patient when it comes to disclosing their diagnosis.
WATCH: Seeking support after a diagnosis.
Sometimes young family members such as children can be incredible motivators for cancer warriors to keep fighting especially when times get tough. Facing cancer as a parent can be daunting. Fearful thoughts about leaving your children may creep into your mind and add even more to your overflowing plate.
“Cancer patients with children can have increased motivation to endure difficult treatment but may also be concerned about the emotional impact of the illness on their offspring,” Dr. Cindy Moore of Massachusetts General Hospital Cancer Center previously explained to The ASCO Post, an oncology newspaper.
During the difficult moments of explaining cancer to younger children, Dr. Moore recommends cancer patients should discuss some of their biggest concerns with their healthcare teams. With the help of your healthcare team, you can come up with an effective communication plan to explain your diagnosis to your kids at an age-appropriate level.
Contributing: SurvivorNet Staff
Learn more about SurvivorNet's rigorous medical review process.