Breast Cancer Clinical Trial

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Determining Molecular Drivers of Radiation Dermatitis

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Summary

This study is being conducted to address key gaps in current knowledge and set the stage for rational design of strategies to prevent (pre-exposure to radiation), mitigate (post-exposure to radiation before overt signs/symptoms appear), and/or treat (post-onset of signs/symptoms) radiation dermatitis (itchy, dry skin or a rash on swollen, reddened skin).

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Eligibility Criteria

Inclusion Criteria:

Patients receiving standard-of-care postoperative radiation therapy (2-2.7 Gy per fraction) to the breast and/or chest wall for breast cancer treatment.
Tissue diagnosis of breast cancer.
Age > 18 years
Signed informed consent.
Complete blood count within normal limits within the preceding 2 weeks.

Exclusion criteria:

Induction chemotherapy or biologic therapy
Concurrent chemotherapy or biologic therapy
Autoimmune disease with skin manifestations - psoriasis, dermatomyositis, scleroderma, eczema, polymyositis
Allergy to lidocaine anesthesia
Known bleeding diathesis (anticoagulation with warfarin, coagulation/bleeding disorders, vitamin C or K deficiency, thrombocytopenia)
History of keloids or easy scarring

Study is for people with:

Breast Cancer

Estimated Enrollment:

20

Study ID:

NCT04764682

Recruitment Status:

Recruiting

Sponsor:

Mayo Clinic

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There is 1 Location for this study

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Mayo Clinic
Jacksonville Florida, 32224, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

20

Study ID:

NCT04764682

Recruitment Status:

Recruiting

Sponsor:


Mayo Clinic

How clear is this clinincal trial information?

Clinical Trial Resources

SurvivorNet’s Guide To Clinical Trials: What Are They And Are They Right for You?
Clinical Trials for Breast Cancer
Have You Been Diagnosed With Late-Stage Breast Cancer? Know That You Have Treatment Options.
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