Chronic Lymphocytic Leukemia Clinical Trial

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A Study to Evaluate the Safety and Efficacy of Ublituximab in Combination With Umbralisib for Participants Previously Enrolled in Protocol UTX-TGR-304

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Summary

This is a multi-center, open-label, study to evaluate the safety and efficacy of ublituximab (TG-1101) in combination with TGR-1202 for patients who have progressed on treatment arms previously enrolled in Protocol UTX-TGR-304

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Eligibility Criteria

Inclusion Criteria:

Prior treatment in clinical trial UTX-TGR-304
Eastern Cooperative Oncology Group (ECOG) score of 0 to 2

Exclusion Criteria:

Participants refractory to ublituximab + TGR-1202
Transformation of leukemia-cll/" >chronic lymphocytic leukemia (CLL) to aggressive Non-Hodgkin's Lymphoma (NHL) (Richter's transformation)

Study is for people with:

Chronic Lymphocytic Leukemia

Phase:

Phase 2

Estimated Enrollment:

116

Study ID:

NCT02656303

Recruitment Status:

Terminated

Sponsor:

TG Therapeutics, Inc.

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There are 87 Locations for this study

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TG Therapeutics Investigational Trial Site
Huntsville Alabama, 35805, United States
TG Therapeutics Investigational Trial Site
Chandler Arizona, 85224, United States
TG Therapeutics Investigational Trial Site
Fayetteville Arkansas, 72703, United States
TG Therapeutics Investigational Trial Site
Duarte California, 91010, United States
TG Therapeutics Investigational Trial Site
Pleasanton California, 94588, United States
TG Therapeutics Investigational Trial Site
San Diego California, 92108, United States
TG Therapeutics Investigational Trial Site
Whittier California, 90603, United States
TG Therapeutics Investigational Trial Site
Aurora Colorado, 80012, United States
TG Therapeutics Investigational Trial Site
Denver Colorado, 80218, United States
TG Therapeutics Investigational Trial Site
Bridgeport Connecticut, 06606, United States
TG Therapeutics Investigational Trial Site
New Haven Connecticut, 06519, United States
TG Therapeutics Investigational Trial Site
Stamford Connecticut, 06904, United States
TG Therapeutics Investigational Trial Site
Newark Delaware, 19713, United States
TG Therapeutics Investigational Trial Site
Boca Raton Florida, 33486, United States
TG Therapeutics Investigational Trial Site
Fort Myers Florida, 33916, United States
TG Therapeutics Investigational Trial Site
Jacksonville Florida, 32204, United States
TG Therapeutics Investigational Trial Site
Jacksonville Florida, 32256, United States
TG Therapeutics Investigational Trial Site
Saint Petersburg Florida, 33705, United States
TG Therapeutics Investigational Trial Site
Tallahassee Florida, 32308, United States
TG Therapeutics Investigational Trial Site
West Palm Beach Florida, 33401, United States
TG Therapeutics Investigational Trial Site
Albany Georgia, 31701, United States
TG Therapeutics Investigational Trial Site
Chicago Illinois, 60612, United States
TG Therapeutics Investigational Trial Site
Peoria Illinois, 61615, United States
TG Therapeutics Investigational Trial Site
Swansea Illinois, 62526, United States
TG Therapeutics Investigational Trial Site
Urbana Illinois, 61801, United States
TG Therapeutics Investigational Trial Site
Fort Wayne Indiana, 46804, United States
TG Therapeutics Investigational Trial Site
Indianapolis Indiana, 46237, United States
TG Therapeutics Investigational Trial Site
Westwood Kansas, 66210, United States
TG Therapeutics Investigational Trial Site
Louisville Kentucky, 40207, United States
TG Therapeutics Investigational Trial Site
Worcester Massachusetts, 01608, United States
TG Therapeutics Investigational Trial Site
Ann Arbor Michigan, 48197, United States
TG Therapeutics Investigational Trial Site
Detroit Michigan, 48202, United States
TG Therapeutics Investigational Trial Site
Jackson Michigan, 49201, United States
TG Therapeutics Investigational Trial Site
Saint Louis Park Minnesota, 55416, United States
TG Therapeutics Investigational Trial Site
Kansas City Missouri, 64132, United States
TG Therapeutics Investigational Trial Site
Lincoln Nebraska, 68510, United States
TG Therapeutics Investigational Trial Site
Lebanon New Hampshire, 03756, United States
TG Therapeutics Investigational Trial Site
Morristown New Jersey, 07932, United States
TG Therapeutics Investigational Trial Site
Glens Falls New York, 12801, United States
TG Therapeutics Investigational Trial Site
Syracuse New York, 13210, United States
TG Therapeutics Investigational Trial Site
Charlotte North Carolina, 28204, United States
TG Therapeutics Investigational Trial Site
Durham North Carolina, 27705, United States
TG Therapeutics Investigational Trial Site
Durham North Carolina, 27710, United States
TG Therapeutics Investigational Trial Site
Hickory North Carolina, 28602, United States
TG Therapeutics Investigational Trial Site
Kinston North Carolina, 28501, United States
TG Therapeutics Investigational Trial Site
Washington North Carolina, 27889, United States
TG Therapeutics Investigational Trial Site
Canton Ohio, 44718, United States
TG Therapeutics Investigational Trial Site
Toledo Ohio, 43623, United States
TG Therapeutics Investigational Trial Site
Portland Oregon, 97227, United States
TG Therapeutics Investigational Trial Site
Portland Oregon, 98684, United States
TG Therapeutics Investigational Trial Site
Springfield Oregon, 97477, United States
TG Therapeutics Investigational Trial Site
Camp Hill Pennsylvania, 17011, United States
TG Therapeutics Investigational Trial Site
Hershey Pennsylvania, 17033, United States
TG Therapeutics Investigational Trial Site
Philadelphia Pennsylvania, 19106, United States
TG Therapeutics Investigational Trial Site
Pittsburgh Pennsylvania, 15224, United States
TG Therapeutics Investigational Trial Site
Pawtucket Rhode Island, 02860, United States
TG Therapeutics Investigational Trial Site
Greenville South Carolina, 29605, United States
TG Therapeutics Investigational Trial Site
Sioux Falls South Dakota, 57105, United States
TG Therapeutics Investigational Trial Site
Chattanooga Tennessee, 37404, United States
TG Therapeutics Investigational Trial Site
Nashville Tennessee, 37203, United States
TG Therapeutics Investigational Trial Site
Fort Worth Texas, 76104, United States
TG Therapeutics Investigational Trial Site
San Antonio Texas, 78240, United States
TG Therapeutics Investigational Trial Site
Ogden Utah, 84405, United States
TG Therapeutics Investigational Trial Site
Blacksburg Virginia, 24060, United States
TG Therapeutics Investigational Trial Site
Charlottesville Virginia, 22908, United States
TG Therapeutics Investigational Trial Site
Fort Belvoir Virginia, 22060, United States
TG Therapeutics Investigational Trial Site
Seattle Washington, 98109, United States
TG Therapeutics Investigational Trial Site
Spokane Washington, 99216, United States
TG Therapeutics Investigational Trial Site
Wauwatosa Wisconsin, 53226, United States
TG Therapeutics Investigational Trial Site
Ferrara , 44020, Italy
TG Therapeutics Investigational Trial Site
Milan , 20132, Italy
TG Therapeutics Investigational Trial Site
Milan , 20141, Italy
TG Therapeutics Investigational Trial Site
Torino , 10126, Italy
TG Therapeutics Investigational Trial Site
Chorzów , 41-50, Poland
TG Therapeutics Investigational Trial Site
Gdynia , 81-51, Poland
TG Therapeutics Investigational Trial Site
Kraków , 30-51, Poland
TG Therapeutics Investigational Trial Site
Lublin , 20-09, Poland
TG Therapeutics Investigational Trial Site
SÅ‚upsk , 76-20, Poland
TG Therapeutics Investigational Trial Site
Warszawa , 02-10, Poland
TG Therapeutics Investigational Trial Site
Warszawa , 02-77, Poland
TG Therapeutics Investigational Trial Site
Warszawa , 02-78, Poland
TG Therapeutics Investigational Trial Site
Warszawa , 50-36, Poland
TG Therapeutics Investigational Trial Site
Łódź , 93-51, Poland
TG Therapeutics Investigational Trial Site
London , SW170, United Kingdom
TG Therapeutics Investigational Trial Site
Norwich , NR47U, United Kingdom
TG Therapeutics Investigational Trial Site
Sunderland , SR47T, United Kingdom
TG Therapeutics Investigational Trial Site
Wolverhampton , WV100, United Kingdom
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How clear is this clinincal trial information?

Study is for people with:

Chronic Lymphocytic Leukemia

Phase:

Phase 2

Estimated Enrollment:

116

Study ID:

NCT02656303

Recruitment Status:

Terminated

Sponsor:


TG Therapeutics, Inc.

How clear is this clinincal trial information?

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