Chronic Lymphocytic Leukemia Clinical Trial

Clinical Trial Finder Chronic Lymphocytic Leukemia Trials

Ublituximab + TGR-1202 Compared to Obinutuzumab + Chlorambucil in Patients With Untreated and Previously Treated Chronic Lymphocytic Leukemia

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Summary

This study evaluates the combination of ublituximab, a novel monoclonal antibody, and TGR-1202, a novel PI3K delta inhibitor compared to obinutuzumab and chlorambucil, and compared to ublituximab or TGR-1202 alone in Chronic Lymphocytic Leukemia (leukemia-cll/" >CLL) patients.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Treatment naïve or previously treated Chronic Lymphocytic Leukemia (CLL) requiring treatment
Eastern Cooperative Oncology Group (ECOG) score of 0 to 2

Exclusion Criteria:

Any major surgery, chemotherapy or immunotherapy within the last 21 days
Evidence of hepatitis B virus, hepatitis C virus or known HIV infection
Autologous hematologic stem cell transplant within 3 months of study entry. Prior Allogeneic hematologic stem cell transplant is excluded
Transformation of CLL to aggressive Non-Hodgkin's Lymphoma (NHL) (Richter's transformation)
Prior therapy with obinutuzumab and/or chlorambucil or a PI3K delta inhibitor

Study is for people with:

Chronic Lymphocytic Leukemia

Phase:

Phase 3

Estimated Enrollment:

603

Study ID:

NCT02612311

Recruitment Status:

Completed

Sponsor:

TG Therapeutics, Inc.

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There are 106 Locations for this study

See Locations Near You

TG Therapeutics Investigational Trial Site
Huntsville Alabama, 35805, United States
TG Therapeutics Investigational Trial Site
Mobile Alabama, 36604, United States
TG Therapeutics Investigational Trial Site
Chandler Arizona, 85224, United States
TG Therapeutics Investigational Trial Site
Phoenix Arizona, 85016, United States
TG Therapeutics Investigational Trial Site
Tucson Arizona, 85711, United States
TG Therapeutics Investigational Trial Site
Fayetteville Arkansas, 72703, United States
TG Therapeutics Investigational Trial Site
Concord California, 94520, United States
TG Therapeutics Investigational Trial Site
Duarte California, 91010, United States
TG Therapeutics Investigational Trial Site
Greenbrae California, 94904, United States
TG Therapeutics Investigational Trial Site
Pismo Beach California, 93449, United States
TG Therapeutics Investigational Trial Site
Pleasanton California, 94588, United States
TG Therapeutics Investigational Trial Site
San Diego California, 92120, United States
TG Therapeutics Investigational Trial Site
Santa Barbara California, 93105, United States
TG Therapeutics Investigational Trial Site
Whittier California, 90603, United States
TG Therapeutics Investigational Trial Site
Aurora Colorado, 80012, United States
TG Therapeutics Investigational Trial Site
Denver Colorado, 80218, United States
TG Therapeutics Investigational Trial Site
Bridgeport Connecticut, 06606, United States
TG Therapeutics Investigational Trial Site
New Haven Connecticut, 06519, United States
TG Therapeutics Investigational Trial Site
Stamford Connecticut, 06904, United States
TG Therapeutics Investigational Trial Site
Newark Delaware, 19713, United States
TG Therapeutics Investigational Trial Site
Boca Raton Florida, 33486, United States
TG Therapeutics Investigational Trial Site
Fort Myers Florida, 33916, United States
TG Therapeutics Investigational Trial Site
Jacksonville Florida, 32204, United States
TG Therapeutics Investigational Trial Site
Jacksonville Florida, 32256, United States
TG Therapeutics Investigational Trial Site
Ocala Florida, 34471, United States
TG Therapeutics Investigational Trial Site
Pensacola Florida, 32504, United States
TG Therapeutics Investigational Trial Site
Saint Petersburg Florida, 33705, United States
TG Therapeutics Investigational Trial Site
Tallahassee Florida, 32308, United States
TG Therapeutics Investigational Trial Site
Tampa Florida, 33612, United States
TG Therapeutics Investigational Trial Site
West Palm Beach Florida, 33407, United States
TG Therapeutics Investigational Trial Site
Albany Georgia, 31701, United States
TG Therapeutics Investigational Trial Site
Macon Georgia, 31201, United States
TG Therapeutics Investigational Trial Site
Chicago Illinois, 60612, United States
TG Therapeutics Investigational Trial Site
Decatur Illinois, 62526, United States
TG Therapeutics Investigational Trial Site
Maywood Illinois, 60153, United States
TG Therapeutics Investigational Trial Site
Niles Illinois, 60714, United States
TG Therapeutics Investigational Trial Site
Peoria Illinois, 61615, United States
TG Therapeutics Investigational Trial Site
Swansea Illinois, , United States
TG Therapeutics Investigational Trial Site
Urbana Illinois, 61801, United States
TG Therapeutics Investigational Trial Site
Fort Wayne Indiana, 46804, United States
TG Therapeutics Investigational Trial Site
Indianapolis Indiana, 46237, United States
TG Therapeutics Investigational Trial Site
Ames Iowa, 50010, United States
TG Therapeutics Investigational Trial Site
Cedar Rapids Iowa, 52403, United States
TG Therapeutics Investigational Trial Site
Kansas City Kansas, 64132, United States
TG Therapeutics Investigational Trial Site
Westwood Kansas, 66210, United States
TG Therapeutics Investigational Trial Site
Louisville Kentucky, 40207, United States
TG Therapeutics Investigational Trial Site
Baltimore Maryland, 21202, United States
TG Therapeutics Investigational Trial Site
Baltimore Maryland, 21215, United States
TG Therapeutics Investigational Trial Site
Bethesda Maryland, 20817, United States
TG Therapeutics Investigational Trial Site
Columbia Maryland, 21044, United States
TG Therapeutics Investigational Trial Site
Boston Massachusetts, 02111, United States
TG Therapeutics Investigational Trial Site
Worcester Massachusetts, 01608, United States
TG Therapeutics Investigational Trial Site
Ann Arbor Michigan, 48106, United States
TG Therapeutics Investigational Trial Site
Detroit Michigan, 48202, United States
TG Therapeutics Investigational Trial Site
Jackson Michigan, 49201, United States
TG Therapeutics Investigational Trial Site
Saint Louis Park Minnesota, 55416, United States
TG Therapeutics Investigational Trial Site
Columbia Missouri, 65212, United States
TG Therapeutics Investigational Trial Site
Kansas City Missouri, , United States
TG Therapeutics Investigational Trial Site
Lincoln Nebraska, 68510, United States
TG Therapeutics Investigational Trial Site
Las Vegas Nevada, 89119, United States
TG Therapeutics Investigational Trial Site
Lebanon New Hampshire, 03756, United States
TG Therapeutics Investigational Trial Site
Morristown New Jersey, 07962, United States
TG Therapeutics Investigational Trial Site
Somerville New Jersey, 00876, United States
TG Therapeutics Investigational Trial Site
East Setauket New York, 11733, United States
TG Therapeutics Investigational Trial Site
Glens Falls New York, 12801, United States
TG Therapeutics Investigational Trial Site
Syracuse New York, 13210, United States
TG Therapeutics Investigational Trial Site
Charlotte North Carolina, 28204, United States
TG Therapeutics Investigational Trial Site
Durham North Carolina, 27710, United States
TG Therapeutics Investigational Trial Site
Durham North Carolina, , United States
TG Therapeutics Investigational Trial Site
Hickory North Carolina, 28602, United States
TG Therapeutics Investigational Trial Site
Kinston North Carolina, 28501, United States
TG Therapeutics Investigational Trial Site
Raleigh North Carolina, 27607, United States
TG Therapeutics Investigational Trial Site
Washington North Carolina, 27889, United States
TG Therapeutics Investigational Trial Site
Canton Ohio, 44718, United States
TG Therapeutics Investigational Trial Site
Cincinnati Ohio, 45236, United States
TG Therapeutics Investigational Trial Site
Toledo Ohio, 43623, United States
TG Therapeutics Investigational Trial Site
Portland Oregon, 97227, United States
TG Therapeutics Investigational Trial Site
Portland Oregon, 97239, United States
TG Therapeutics Investigational Trial Site
Springfield Oregon, 97477, United States
TG Therapeutics Investigational Trial Site
Camp Hill Pennsylvania, 17011, United States
TG Therapeutics Investigational Trial Site
Danville Pennsylvania, 17822, United States
TG Therapeutics Investigational Trial Site
Hershey Pennsylvania, 17033, United States
TG Therapeutics Investigational Trial Site
Philadelphia Pennsylvania, 19106, United States
TG Therapeutics Investigational Trial Site
Pittsburgh Pennsylvania, 15224, United States
TG Therapeutics Investigational Trial Site
Pittsburgh Pennsylvania, 15232, United States
TG Therapeutics Investigational Trial Site
Pawtucket Rhode Island, 00286, United States
TG Therapeutics Investigational Trial Site
Greenville South Carolina, 29615, United States
TG Therapeutics Investigational Trial Site
Sioux Falls South Dakota, 57105, United States
TG Therapeutics Investigational Trial Site
Watertown South Dakota, 57201, United States
TG Therapeutics Investigational Trial Site
Chattanooga Tennessee, 37404, United States
TG Therapeutics Investigational Trial Site
Nashville Tennessee, 37203, United States
TG Therapeutics Investigational Trial Site
Austin Texas, 78705, United States
TG Therapeutics Investigational Trial Site
Bedford Texas, 76022, United States
TG Therapeutics Investigational Trial Site
Fort Worth Texas, 76104, United States
TG Therapeutics Investigational Trial Site
Houston Texas, 77030, United States
TG Therapeutics Investigational Trial Site
San Antonio Texas, 78217, United States
TG Therapeutics Investigational Trial Site
San Antonio Texas, 78229, United States
TG Therapeutics Investigational Trial Site
Tyler Texas, 75702, United States
TG Therapeutics Investigational Trial Site
Ogden Utah, 84405, United States
TG Therapeutics Investigational Trial Site
Blacksburg Virginia, 24060, United States
TG Therapeutics Investigational Trial Site
Charlottesville Virginia, 22908, United States
TG Therapeutics Investigational Trial Site
Fort Belvoir Virginia, 22060, United States
TG Therapeutics Investigational Trial Site
Olympia Washington, 98502, United States
TG Therapeutics Investigational Trial Site
Seattle Washington, 98104, United States
TG Therapeutics Investigational Trial Site
Seattle Washington, 98109, United States
TG Therapeutics Investigational Trial Site
Spokane Washington, 99216, United States
TG Therapeutics Investigational Trial Site
Vancouver Washington, 98684, United States
TG Therapeutics Investigational Trial Site
Yakima Washington, 98902, United States
TG Therapeutics Investigational Trial Site
Milwaukee Wisconsin, 53226, United States
TG Therapeutics Investigational Trial Site
Wauwatosa Wisconsin, 53226, United States
TG Therapeutics Investigational Trial Site
Ashkelon , , Israel
TG Therapeutics Investigational Trial Site
Be'er Sheva , , Israel
TG Therapeutics Investigational Trial Site
Haifa , , Israel
TG Therapeutics Investigational Trial Site
Jerusalem , , Israel
TG Therapeutics Investigational Trial Site
Nahariya , , Israel
TG Therapeutics Investigational Trial Site
Petah tikva , , Israel
TG Therapeutics Investigational Trial Site
Tel Aviv , , Israel
TG Therapeutics Investigational Trial Site
Bologna , , Italy
TG Therapeutics Investigational Trial Site
Ferrara , , Italy
TG Therapeutics Investigational Trial Site
Milan , , Italy
TG Therapeutics Investigational Trial Site
Rome , , Italy
TG Therapeutics Investigational Trial Site
Torino , , Italy
TG Therapeutics Investigational Trial Site
Chorzów , , Poland
TG Therapeutics Investigational Trial Site
Gdynia , , Poland
TG Therapeutics Investigational Trial Site
Krakow , , Poland
TG Therapeutics Investigational Trial Site
Lublin , , Poland
TG Therapeutics Investigational Trial Site
SÅ‚upsk , , Poland
TG Therapeutics Investigational Trial Site
Warszawa , , Poland
TG Therapeutics Investigational Trial Site
Wroclaw , , Poland
TG Therapeutics Investigational Trial Site
Łódź , , Poland
TG Therapeutics Investigational Trial Site
Krasnozatonskiy , , Russian Federation
TG Therapeutics Investigational Trial Site
Moscow , , Russian Federation
TG Therapeutics Investigational Trial Site
Perm , , Russian Federation
TG Therapeutics Investigational Trial Site
Petrozavodsk , , Russian Federation
TG Therapeutics Investigational Trial Site
Rodionova , , Russian Federation
TG Therapeutics Investigational Trial Site
Saint Petersburg , , Russian Federation
TG Therapeutics Investigational Trial Site
Smolensk , , Russian Federation
TG Therapeutics Investigational Trial Site
Tula , , Russian Federation
TG Therapeutics Investigational Trial Site
Yaroslavl , , Russian Federation
TG Therapeutics Investigational Trial Site
Barcelona , , Spain
TG Therapeutics Investigational Trial Site
Madrid , , Spain
TG Therapeutics Investigational Trial Site
Valencia , , Spain
TG Therapeutics Investigational Trial Site
Cambridge , , United Kingdom
TG Therapeutics Investigational Trial Site
Cumbria , , United Kingdom
TG Therapeutics Investigational Trial Site
Dudley West , , United Kingdom
TG Therapeutics Investigational Trial Site
London , , United Kingdom
TG Therapeutics Investigational Trial Site
Northbrook , , United Kingdom
TG Therapeutics Investigational Trial Site
Northumbria , , United Kingdom
TG Therapeutics Investigational Trial Site
Norwich , , United Kingdom
TG Therapeutics Investigational Trial Site
Peterborough , , United Kingdom
TG Therapeutics Investigational Trial Site
Southampton , , United Kingdom
TG Therapeutics Investigational Trial Site
St. James , , United Kingdom
TG Therapeutics Investigational Trial Site
Sunderland , , United Kingdom
TG Therapeutics Investigational Trial Site
Wolverhampton , , United Kingdom
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How clear is this clinincal trial information?

Study is for people with:

Chronic Lymphocytic Leukemia

Phase:

Phase 3

Estimated Enrollment:

603

Study ID:

NCT02612311

Recruitment Status:

Completed

Sponsor:


TG Therapeutics, Inc.

How clear is this clinincal trial information?

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