Kidney Cancer Clinical Trial
Serial Ultrasound in Metastatic Renal Cell Carcinoma (mRCC)
Summary
To assess whether changes in quantitative tumor perfusion parameters after 3 weeks of treatment, as measured by power doppler ultrasound, can predict initial objective response, defined by current standard-of-care, to therapy at 12 weeks after start of treatment
Eligibility Criteria
Inclusion Criteria:
18 years of age or older
Pathology-confirmed diagnosis of metastatic RCC
At least one tumor lesion greater than 1 cm in diameter, amenable to ultrasound imaging
Written informed consent.
Specific inclusion criteria:
arm 1: planned to be treated with combination of VEGFR2 tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI)
arm 2: planned to be treated with non-ICI therapy
Exclusion Criteria:
-Any comorbid condition that, in the opinion of the treating provider or the Protocol Directors, compromises the participant's ability to participate in the study
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There is 1 Location for this study
Stanford California, 94305, United States
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