Lung Cancer Clinical Trial

Validation of a Multi-gene Test for Lung Cancer Risk

Summary

The purpose of this study is to determine the validity of a multi-gene Lung Cancer Risk Test (LCRT). In the process, the investigators will establish a bank of NBEC samples and corresponding blood samples from individuals demographically at increased risk for lung cancer.

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Full Description

Because more than 160,000 individuals die of lung cancer/year in the United States alone, it is important to use the best possible methods to determine whether increased surveillance of individuals at highest risk for lung cancer will result in reduced lung cancer mortality. The Lung Cancer Risk Test (LCRT) proposed for evaluation promises to accurately identify the 10-15% of the population that is most susceptible to lung cancer based on genetic predisposition. More than 90 million individuals in the United States alone are demographically at high risk for lung cancer and potential candidates for increased surveillance.

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Eligibility Criteria

Inclusion Criteria:

20 or more pack year smoking history
clinical need for diagnostic bronchoscopy or consent to study driven bronchoscopy

Exclusion Criteria:

Lung Cancer within 3 months after the date of enrollment

Study is for people with:

Lung Cancer

Estimated Enrollment:

403

Study ID:

NCT01130285

Recruitment Status:

Active, not recruiting

Sponsor:

University of Toledo Health Science Campus

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There are 12 Locations for this study

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National Jewish Health
Denver Colorado, 80206, United States
University of Michigan
Ann Arbor Michigan, 48109, United States
Henry Ford
Detroit Michigan, 48202, United States
Mayo Clinic
Rochester Minnesota, 55905, United States
Cleveland Clinic Foundation
Cleveland Ohio, 44195, United States
Ohio State University
Columbus Ohio, 43221, United States
The Toledo Hospital
Toledo Ohio, 43606, United States
Mercy St. Vincent Medical Center
Toledo Ohio, 43608, United States
University of Toledo, Health Science Campus
Toledo Ohio, 43614, United States
Medical University of South Carolina
Charleston South Carolina, 29425, United States
Tennessee Valley Veterans Admin.
Nashville Tennessee, 37232, United States
Vanderbilt
Nashville Tennessee, 37232, United States
Inova Fairfax Hospital
Falls Church Virginia, 22042, United States

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Estimated Enrollment:

403

Study ID:

NCT01130285

Recruitment Status:

Active, not recruiting

Sponsor:


University of Toledo Health Science Campus

How clear is this clinincal trial information?

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