Melanoma Clinical Trial

Clinical Trial Finder Melanoma Trials

A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

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Summary

The purpose of this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab by itself in treating unresectable melanoma or melanoma that has spread.

View Eligibility Criteria

Eligibility Criteria

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com

Inclusion Criteria:

Participants must have histologically confirmed Stage III (unresectable) or Stage IV melanoma, per the AJCC staging system
Participants must not have had prior systemic anticancer therapy for unresectable or metastatic melanoma
Tumor tissue from an unresectable or metastatic site of disease must be provided for biomarker analyses

Exclusion Criteria:

Participants must not have active brain metastases or leptomeningeal metastases
Participants must not have uveal melanoma
Participants must not have an active, known, or suspected autoimmune disease

Other protocol defined inclusion/exclusion criteria could apply

Study is for people with:

Melanoma

Phase:

Phase 2

Estimated Enrollment:

714

Study ID:

NCT03470922

Recruitment Status:

Active, not recruiting

Sponsor:

Bristol-Myers Squibb

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There are 124 Locations for this study

See Locations Near You

Local Institution - 0010
Tucson Arizona, 85724, United States
Local Institution - 0020
Los Angeles California, 90095, United States
Coastal Integrative Cancer Care
San Luis Obispo California, 93401, United States
Local Institution - 0116
Santa Barbara California, 93105, United States
Local Institution - 0012
Washington District of Columbia, 20007, United States
Local Institution - 0013
Jacksonville Florida, 32224, United States
Local Institution - 0117
Orlando Florida, 32806, United States
Local Institution - 0007
Tampa Florida, 33612, United States
Local Institution - 0038
Atlanta Georgia, 30342, United States
Local Institution - 0016
Chicago Illinois, 60611, United States
Local Institution - 0114
Fort Wayne Indiana, 46804, United States
Local Institution - 0077
Baltimore Maryland, 21237, United States
Local Institution - 0120
Baltimore Maryland, 21287, United States
Local Institution - 0014
Boston Massachusetts, 02215, United States
Local Institution - 0134
Boston Massachusetts, 02215, United States
Local Institution - 0015
Ann Arbor Michigan, 48109, United States
Local Institution - 0009
Minneapolis Minnesota, 55407, United States
Local Institution - 0011
Rochester Minnesota, 55905, United States
Local Institution - 0018
Charlotte North Carolina, 28204, United States
Local Institution - 0019
Allentown Pennsylvania, 18103, United States
Local Institution - 0076
Dallas Texas, 75246, United States
Local Institution - 0008
Houston Texas, 77030, United States
Local Institution - 0135
Buenos Aires Distrito Federal, 1121, Argentina
Local Institution - 0002
Capital Federal Distrito Federal, C1280, Argentina
Local Institution - 0004
Buenos Aires , 1199, Argentina
Local Institution - 0005
Buenos Aires , 4102-, Argentina
Local Institution - 0003
Ciudad Autónoma De Buenos Aires , 1426, Argentina
Local Institution - 0042
North Sydney New South Wales, 2060, Australia
Local Institution - 0043
Waratah New South Wales, 2298, Australia
Local Institution - 0041
Greenslopes Queensland, 4120, Australia
Local Institution - 0045
Southport Queensland, 4215, Australia
Local Institution - 0133
Bedford Park South Australia, 5042, Australia
Local Institution - 0044
Murdoch Western Australia, 6150, Australia
Local Institution - 0036
Graz , 8036, Austria
Local Institution - 0037
Salzburg , 5020, Austria
Local Institution - 0035
Wien , 1090, Austria
Local Institution - 0047
Brussels , 1090, Belgium
Local Institution - 0049
Bruxelles , 1200, Belgium
Local Institution - 0048
Gent , 9000, Belgium
Local Institution - 0058
Belo Horizonte Minas Gerais, 30130, Brazil
Local Institution - 0057
Porto Alegre RIO Grande DO SUL, 90035, Brazil
Local Institution - 0061
Porto Alegre RIO Grande DO SUL, 91350, Brazil
Local Institution - 0073
Santa Cruz do Sul RIO Grande DO SUL, 96810, Brazil
Local Institution - 0063
São Paulo SAO Paulo, 05651, Brazil
Local Institution - 0059
Rio De Janiro , 20220, Brazil
Local Institution - 0060
Sao Paulo , 01246, Brazil
Local Institution - 0062
Sao Paulo , 01509, Brazil
Local Institution - 0124
Halifax Nova Scotia, B3H 2, Canada
Local Institution - 0068
Ottawa Ontario, K1H 8, Canada
Local Institution - 0128
Toronto Ontario, M5G 2, Canada
Local Institution - 0123
Montreal Quebec, H3T 1, Canada
Local Institution - 0075
Montreal Quebec, H4A 3, Canada
Local Institution - 0001
Santiago Metropolitana, , Chile
Local Institution - 0096
Medellín Antioquia, 05003, Colombia
Local Institution - 0095
Bogota , 11032, Colombia
Local Institution - 0105
Aarhus N , 8200, Denmark
Local Institution - 0103
Herlev , 2730, Denmark
Local Institution - 0104
Odense , 5000, Denmark
Local Institution - 0100
Helsinki Uusimaa, 00290, Finland
Local Institution - 0102
Oulu , 90220, Finland
Local Institution - 0119
Tampere , 33521, Finland
Local Institution - 0101
Turku , 20520, Finland
Local Institution - 0084
Rennes Ille-et-Vilaine, 35042, France
Local Institution - 0079
Amiens Somme, 80000, France
Local Institution - 0080
Bordeaux Cedex , 33075, France
Local Institution - 0085
Lille , 59000, France
Local Institution - 0081
Marseille , 13011, France
Local Institution - 0083
Paris , 75010, France
Local Institution - 0078
Pierre-Benite , 69310, France
Local Institution - 0082
Poitiers , 86000, France
Local Institution - 0131
Tübingen Baden-Württemberg, 72076, Germany
Local Institution - 0071
Quedlinburg Sachsen-Anhalt, 06484, Germany
Local Institution - 0032
Buxtehude , 21614, Germany
Local Institution - 0030
Erfurt , 99089, Germany
Local Institution - 0027
Essen , 45147, Germany
Local Institution - 0033
Hannover , 30625, Germany
Local Institution - 0132
Heidelberg , 69120, Germany
Local Institution - 0074
Homburg / Saar , 66421, Germany
Local Institution - 0029
Köln , 50937, Germany
Local Institution - 0028
Lubeck , 23538, Germany
Local Institution - 0072
Mannheim , 68167, Germany
Local Institution - 0034
Muenchen , 81675, Germany
Local Institution - 0031
Wuerzburg , 97080, Germany
Local Institution - 0064
Athens , 11526, Greece
Local Institution - 0065
Thessaloniki , 54622, Greece
Local Institution - 0086
Haifa , 31096, Israel
Local Institution - 0088
Jerusalem , 91120, Israel
Local Institution - 0087
Ramat-gan , 52621, Israel
Local Institution - 0111
Torino Piemonte, 10126, Italy
ASST Papa Giovanni XXIII - Azienda Ospedaliera Papa Giovanni XXIII
Bergamo , 24127, Italy
Local Institution - 0108
Milano , 20133, Italy
Istituto Nazionale Tumori Fondazione Pascale
Napoli , 80131, Italy
Istituto Oncologico Veneto IOV
Padova , 35128, Italy
AOUS - Policlinico S.Maria Alle Scotte
Siena , 53100, Italy
Local Institution - 0094
Zapopan Jalisco, 45070, Mexico
Local Institution - 0091
Monterrey Nuevo LEON, 64060, Mexico
Local Institution - 0093
Cancún Quintana Roo, 77500, Mexico
Local Institution - 0092
Merida Yucatan, 97134, Mexico
Local Institution - 0129
Veracruz , 91900, Mexico
Local Institution - 0090
Dunedin , 9012, New Zealand
Local Institution - 0125
Hamilton , 3240, New Zealand
Local Institution - 0089
Tauranga , 3112, New Zealand
Local Institution - 0121
Oslo , 0310, Norway
Local Institution - 0040
Poznan Wielkopolskie, 60-78, Poland
Local Institution - 0039
Warszawa , 02-78, Poland
Local Institution - 0070
Cluj-Napoca Cluj, 40001, Romania
Local Institution - 0066
Bucharest ,  , Romania
Local Institution - 0067
Craiova , 20054, Romania
Local Institution - 0069
Iasi , 70048, Romania
Local Institution - 0113
Krasnodar , 35004, Russian Federation
Local Institution - 0127
Krasnoyarsk , 66013, Russian Federation
Local Institution - 0112
Moscow , 11547, Russian Federation
Local Institution - 0023
A Coruña , 15006, Spain
Local Institution - 0024
Barcelona , 08035, Spain
Local Institution - 0025
Barcelona , 08036, Spain
Local Institution - 0026
Madrid , 28034, Spain
Local Institution - 0021
San Sabastian Gipuzkoa , 20014, Spain
Local Institution - 0022
Sevilla , 41009, Spain
Local Institution - 0098
Goteborg , 413 4, Sweden
Local Institution - 0099
Lund , 221 8, Sweden
Local Institution - 0118
Solna , 171 6, Sweden
Local Institution - 0122
Uppsala , 751 8, Sweden
Local Institution - 0052
Bristol Avon, BS2 8, United Kingdom
Local Institution - 0054
Glasgow Dumfries & Galloway, G12 0, United Kingdom
Local Institution - 0056
Swansea Glamorgan, SA2 8, United Kingdom
Local Institution - 0051
London Greater London, SE1 9, United Kingdom
Local Institution - 0126
Inverness Inverness-shire, IV2 3, United Kingdom
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How clear is this clinincal trial information?

Study is for people with:

Melanoma

Phase:

Phase 2

Estimated Enrollment:

714

Study ID:

NCT03470922

Recruitment Status:

Active, not recruiting

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

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