Psoriasis Clinical Trial

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COVID-19 Vaccination in Rheumatic Disease Patients

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Summary

The research is being done to study the immune responses to COVID-19 vaccination in patients with rheumatic diseases.

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Full Description

Because patients treated with immunosuppressive agents have been excluded from initial clinical trials, and most patients with rheumatic diseases are taking immunosuppressants, the immune responses towards the mRNA COVID19 vaccines in these patients remains unknown. The goal is to study the immune response to COVID-19 vaccination in patients with rheumatic diseases. Blood samples collected before and longitudinally after mRNA-based COVID-19 vaccination (i.e., Pfizer and Moderna vaccines) will enable detailed immunological investigation of the interaction between COVID-19 vaccination and rheumatic diseases. These efforts will provide novel insights into the COVID-19 vaccine response in patients with rheumatic diseases, and eventually would inform clinical management to improve patient care.

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Eligibility Criteria

Inclusion Criteria:

Rheumatologist confirmed diagnosis of one of the following diagnoses:
Systemic lupus erythematosus;
Sjogren syndrome;
Inflammatory myositis;
Psoriatic arthritis;
Osteoarthritis;
Gout;
Ankylosing spondylitis;
IBD-related arthritis.

Exclusion Criteria:

Active infection or untreated malignancy (other than skin cancer) at enrollment.
Pregnancy

Study is for people with:

Psoriasis

Phase:

Early Phase 1

Estimated Enrollment:

58

Study ID:

NCT04839315

Recruitment Status:

Terminated

Sponsor:

Mayo Clinic

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There is 1 Location for this study

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Mayo Clinic in Rochester
Rochester Minnesota, 55905, United States

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Early Phase 1

Estimated Enrollment:

58

Study ID:

NCT04839315

Recruitment Status:

Terminated

Sponsor:


Mayo Clinic

How clear is this clinincal trial information?

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