Psoriasis Clinical Trial

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Daily Topical Rapamycin for Vitiligo

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Summary

In current Dermatology practice, options for vitiligo remain limited. The purpose of this study is to determine if once daily dosed topical rapamycin is effective for the treatment of patients with vitiligo. Participants will apply either 0.1% topical rapamycin or 0.001% topical rapamycin for six months to a lesion on one side of the body, and topical placebo to a corresponding lesion on the opposite side of the body. The study also aims to evaluate patient satisfaction and identify any adverse effects on these dosing regimens.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Patients 13 years of age and older
Patients with nonsegmental vitiligo

Exclusion Criteria:

Patients with segmental or mucosal vitiligo
Patients with contraindication to use of rapamycin
Patients with history of transplant
Patients with a history of natural immunodeficiency
Patients with a history of artificially induced immunodeficiency
Patients with a history of a serious or life-threatening infection
Patients taking CYP3A4 inhibiting medications
Patients taking strong CYP3A4 inducers
Patients undergoing current treatment for vitiligo
Women that are or may become pregnant

Study is for people with:

Psoriasis

Phase:

Phase 2

Estimated Enrollment:

20

Study ID:

NCT05342519

Recruitment Status:

Active, not recruiting

Sponsor:

Medical University of South Carolina

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There is 1 Location for this study

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Medical University of South Carolina
Charleston South Carolina, 29425, United States

How clear is this clinincal trial information?

Study is for people with:

Psoriasis

Phase:

Phase 2

Estimated Enrollment:

20

Study ID:

NCT05342519

Recruitment Status:

Active, not recruiting

Sponsor:


Medical University of South Carolina

How clear is this clinincal trial information?

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