PTEN and Advanced Prostate Cancer:
Insights From Urologists & Oncologists
SurvivorNet spoke to experts and oncologists to learn what PTEN loss means, how common it is for men with advanced prostate cancer, and why testing for this characteristic is so important now that a new targeted therapy has been approved.
PTEN Loss: Why it Matters
A Move Towards More 'Personalized Medicine'
There are certain characteristics of prostate cancer that will impact treatment approach, including genetic of molecular changes in the tumor. One of these is known as PTEN loss, and it can affect how aggressive cancer is. PTEN is a tumor suppressor gene that helps regulate how cells grow. In prostate cancer, when PTEN... Read More
- About 25% of patients with metastatic hormone-sensitive prostate cancer have what are known as PTEN-deficient tumors, which can be more aggressive.
- There is now a targeted treatment called Truqap (capivasertib) that can help reduce the risk of disease progression.
- Patients should ask their doctors about PTEN testing after diagnosis.
Getting Tested for PTEN-Deficiency
- About 25% of patients with metastatic hormone-sensitive prostate cancer have what are known as PTEN-deficient tumors, which can be more aggressive.
- There is now a targeted treatment called Truqap (capivasertib) that can help reduce the risk of disease progression.
- Patients should ask their doctors about PTEN testing after diagnosis.
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