Finding Your Way Through Multiple Sclerosis
- Country music singer Clay Walker, 55, has lived with multiple sclerosis for 30 years, managing symptoms like balance issues, double vision, and leg weakness while continuing his music career.
- After a dire early prognosis, he found an effective unnamed medication and physical therapy routine that has kept him relapse‑free and helped him control spasticity and pain.
- Multiple sclerosis (MS) is an “immune‑mediated condition,” meaning the immune system mistakenly attacks the body’s own tissues, explains Dr. Lauren Krupp, a neurologist at NYU Langone.
- Although MS does not have a cure, common tools such as wheelchairs, canes, leg braces, and some medical treatments called disease-modifying therapies (DMTs) may improve the quality of life for people living with the disease.
- A study in American Family Physician found that DMTs “have been shown to slow disease progression and disability; options include injectable agents, infusions, and oral medications targeting different sites in the inflammatory pathway.”
The reason isn’t just age. For 30 years, Walker has lived with multiple sclerosis (MS), a chronic condition that affects the brain and central nervous system and can lead to symptoms such as numbness, fatigue, balance issues, blurred vision, and difficulty walking.


At just 26, Walker received a tough prognosis: based on the number of lesions doctors found, he was told he could be using a wheelchair within four years and might not live beyond eight.
“That was a hard prognosis to take,” he later shared with “ChoosePT.”
“I’m thankful and appreciative that it was not the reality, though it very well could have been.”
@claywalker I’m a country music singer… what else would you expect 🤷 #ofcoursetrend #countrymusic #claywalker ♬ original sound – Clay Walker
Finding the right treatment changed everything. Walker says it took time, but eventually he found a medication that drastically reduced any relapse and gave him a new outlook on life.
He also committed to physical therapy, developing a routine of stretches and exercises to quickly relieve spasticity in his spinal cord.
“I’ve been able to work out a certain protocol,” he explained. “I can bust that spasticity in minutes.”
Emotionally, the diagnosis was isolating. Walker says he didn’t know anyone else living with MS at the time he was diagnosed, and the condition can be difficult for others to understand.
“MS is different for everyone,” he says, noting that the unpredictability of symptoms can make the disease especially challenging.
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Over time, Walker chose to make his MS journey part of his public identity. He has become an advocate for the MS community, raising awareness and funds while speaking openly about the realities of the disease — including the pain many people don’t see. He’s grateful that he’s learned how to manage his symptoms without relying on painkillers.
“Every day I wake up, I want to live life a little more fully, a little better,” Walker says.
Expert Resources for Multiple Sclerosis Patients
- ‘Don’t Stop Me Now’ Is Inspiration for Anybody With Multiple Sclerosis
- Newly Diagnosed With Multiple Sclerosis? Understanding Your Treatment Options
- Staying Healthy & Fit While Treating Multiple Sclerosis (MS): A Neurology Expert Weighs In
- Leading Neurologist Highlights How Multiple Sclerosis (MS) Treatment Is Improving Daily Life For Patients
Better Understanding of Multiple Sclerosis
Multiple sclerosis (MS) is an “immune‑mediated condition,” meaning the immune system mistakenly attacks the body’s own tissues, explains Dr. Lauren Krupp, a neurologist at NYU Langone.
“We’re not exactly sure why that happens,” she tells SurvivorNet, “but it probably has to do with exposure to a virus at some point. In the effort to fight off that virus, the immune system turns against itself and specifically targets a coating of the nerves called myelin.”

Myelin protects nerve fibers in the central nervous system, which includes the brain and spinal cord. When it’s damaged, communication between the brain and the rest of the body becomes disrupted.
Since MS can affect different areas of the brain or spinal cord, Dr. Krupp notes, “the symptoms can vary in location.”
Common symptoms include:
- Numbness or tingling in the face
- Numbness or weakness in the arms or legs
- Vertigo or a spinning sensation
- Blurred or lost vision
- Poor coordination
Symptoms may appear on one side of the body or, when the spinal cord is involved, on both. Numbness can spread and may be accompanied by muscle weakness.
The National Institute of Neurological Disorders and Stroke describes MS as “an unpredictable disease of the central nervous system” that can range from relatively mild to significantly disabling, depending on how severely communication between the brain and body is affected. Researchers widely consider it an autoimmune disease.
There is currently no cure for MS, but many people manage the condition with medications, steroid treatments, or, in some cases, chemotherapy‑based therapies designed to calm the immune system and slow disease activity.
Learning to Live With MS
Common tools M.S. patients use to improve their quality of life include wheelchairs, canes, leg braces, and some medical treatments called disease-modifying therapies (DMTs).
A study in American Family Physician found that DMTs “have been shown to slow disease progression and disability; options include injectable agents, infusions, and oral medications targeting different sites in the inflammatory pathway.”
Research published in Frontiers in Neurology last year says autologous hematopoietic stem cell transplantation (AHSCT) (also called bone marrow transplantation, with autologous meaning a patient’s own cells) used for multiple sclerosis therapy helps “reset the immune system.” Several studies and clinical trials using AHSCT have shown promise.
WATCH: SurvivorNetTV Presents: Defying All Odds – A World-Renowned Doctor’s Incredible Journey Through MS
“In a meta-analysis of published studies using AHSCT for M.S. treatment, the pooled estimated transplant-related mortality was 2.1%, the two-year disease progression rate was 17.1%, the five-year progression rate of 23.3%, and a pooled 83% of patients had no evidence of disease activity at two years. Patients who had the most benefit and the least mortality rate were patients with relapsing-remitting M.S. (RRMS).”
Additional research published by NEJM Journal Watch says that AHSCT helps MS patients reduce relapses better than other forms of MS treatment.
The National Multiple Sclerosis Society outlines the different types of multiple sclerosis:
- Clinically isolated syndrome (CIS) is when an individual experiences a single neurological episode lasting 24 hours or less. CIS is what M.S. is diagnosed as until there is a second episode.
- Relapsing-remitting MS (RRMS): The most common M.S. among the million people battling the disease in the U.S., RRMS is marked by sudden flare-ups, new symptoms, or worsening of symptoms and cognitive function. The condition will then go into remission for some time before reemerging with no known warning signs.
- Primary progressive M.S. (PPMS): These individuals have no flare-ups or remission, just a steady decline with progressively worse symptoms and an increasing loss of cognitive and body functions.
- Secondary progressive M.S. (SPMS): This is an almost transitional form of M.S. that progresses from RRMS to PPMS.
Finding Resources And Support
For patients and families navigating MS or another serious illness like a cancer diagnosis, gaining access to new treatment or trials can feel overwhelming. That’s why SurvivorNet encourages patients to use its proprietary Clinical Trial Finder, a free tool designed to help patients identify relevant trials quickly and easily.
Every year, new early-phase studies come online, each one representing another step forward in disease management.
SurvivorNet’s AI-powered “My Health Questions” tool was also built with patient needs in mind, to give patients and their caregivers access to health information vetted by professionals right when they need it.
Questions for Your Doctor
If you are diagnosed with MS or are concerned you have the chronic disease due to symptoms you’re experiencing, consider asking your doctor the following questions.
- Although there’s no cure for MS, which treatment option do you recommend to manage my symptoms?
- Are there any potential side effects of MS treatment?
- What if the treatment to manage symptoms doesn’t work?
- Will exercise or therapy help my symptoms?
- Are there any MS support groups you recommend to help me cope?
Learn more about SurvivorNet's rigorous medical review process.
