Coping With a Breast Cancer Diagnosis & Tough Chemo
- Actress Crystal Lowe, known for “Final Destination 3,” was diagnosed with stage 3 breast cancer despite having no prior major health issues—her body awareness from years in the spotlight helped her catch early warning signs.
- Lowe’s journey began with a persistent breast mass and an inverted nipple, leading to a diagnosis that required chemotherapy, a double mastectomy, and radiation—she described the experience as “scary, strange, and humbling.”
- The U.S. Preventive Services Task Force recommends women begin screening for breast cancer at age 40. Women should talk with their doctor to learn about their cancer risk and assess when it is a good time to start annual mammograms.
- Part of Lowe’s treatment was an aggressive form of chemo called “The Red Devil.” The red devil is a form of chemotherapy that involves anthracyclines, an adjuvant chemotherapy treatment given after surgery. Research published in JACC: CardioOncology says anthracyclines offer a “10% improvement in disease-free survival and a 7% improvement in overall survival, compared with the initial standard regimen.
- A breast cancer diagnosis can spawn a flurry of emotions and impact your mental health. Research published in Epidemiology and Psychiatric Sciences found that “35 to 40 percent of cancer patients have a diagnosable psychiatric disorder,” and patients battling late-stage cancer tend to face even more significant mental health challenges.
- To help manage your mental health while coping with a diagnosis, some helpful tips include leaning on your support group, journaling, and/or seeking a mental health professional.

“I’ve never had any major illness,” Lowe shared, reflecting on the shock of her diagnosis in an essay for People Magazine.
Read MoreBut the relief didn’t last. The mass remained—and began to change in appearance.
“The mass was still there, but it was changing in size and placement, and my confusion (and fear) kept growing. I didn’t feel any pain, but my nipple became inverted, so I went back to the doctor,” Lowe explained.
Her physician’s words were sobering: “Honey, I can’t be sure, but this feels like cancer.” Days later, the diagnosis was confirmed: stage 3 breast cancer.
WATCH: Stage 3 Breast Cancer Explained.
Stage three breast cancer typically refers to a relatively large tumor that may have invaded nearby skin or muscle tissue. It may also mean that lymph nodes near your breast and/or under your armpit are involved. In most cases, stage three breast cancers will need chemotherapy. If the cancer is also hormone receptor-positive, aggressive hormonal therapy may be offered as well.
“I still remember getting off the phone, curling up into a ball, and just bawling,” Lowe recalled.
The emotional toll was immediate, and the treatment plan daunting.

“I’m looking at the whole deal: chemo, double mastectomy, radiation, and, eventually, implants… As someone who’s never had any major illness, it was a lot to digest.”
Chemotherapy proved especially grueling, with side effects ranging from debilitating fatigue to gastrointestinal distress. Yet through the darkness of moments, Lowe found a bright spot in her support system—family, friends, and fellow survivors who rallied around her.
“I am fortunate enough to be surrounded by so much love and support. My husband and family have been my rock. And my friends? They’ve wrapped me up like a blanket — visiting, checking in, cleaning my house, and creating an incredible meal train that has fed my body and my heart,” she said.
Lowe’s vigilance and a keen sense of awareness to listen to her body helped her discover her cancer before it reached more advanced stages. While not every symptom signals cancer, she urges others to seek medical attention for signs such as:
- A new breast lump
- Swelling in one breast
- Nipple changes (like puckering or inversion)
- Redness or flaking of the breast or nipple
- Nipple discharge, including blood
- Breast pain
WATCH: How self-exams can help you learn what’s normal and what’s not for your breasts.
As her cancer journey continues, Lowe describes the experience as “scary, strange, and humbling.” But she remains determined to persevere—not just for herself, but for her children and loved ones.
Helping Patients Cope with Chemotherapy
Lowe Says the ‘Fear Was Indescribable’ Before Beginning Aggressive Chemo
We noted Lowe’s chemotherapy experience earlier. She says she needed an aggressive type of chemotherapy often dubbed “The Red Devil.”
Lowe said before she started her chemo regimen, her “heart raced as the nurse walked toward me with a vial of “The Red Devil.”
“The fear was indescribable,” Lowe said.

The red devil is a form of chemotherapy that involves anthracyclines, an adjuvant chemotherapy treatment given after surgery. Research published in JACC: CardioOncology says anthracyclines offer a “10% improvement in disease-free survival and a 7% improvement in overall survival, compared with the initial standard regimen of cyclophosphamide, methotrexate, and 5-fluorouracil.”
Anthracycline and taxane (a class of chemotherapy drugs) have become a mainstay for breast cancer treatment. However, despite the effectiveness of these chemotherapy drugs, they come with intense side effects such as nausea, vomiting, and alopecia (hair loss), which helped give it its “red devil” nickname.
Managing Chemotherapy and Its Side Effects
Chemotherapy is an effective tool for oncologists to help treat cancer by stopping cancerous cells from growing, dividing, and spreading to other organs. Chemo works by traveling through the bloodstream, killing cancerous cells. However, healthy cells are also impacted in the process, leading to side effects.
Patients almost universally experience fatigue, often alongside gastrointestinal side effects, such as nausea. Doctors have many effective medications to combat chemo-induced nausea. “But mitigating that fatigue often depends on the patient,” says Dr. Renata Urban, a gynecologic oncologist at the University of Washington in Seattle.
“Neuropathy is probably one of the most challenging side effects,” says Dr. Renata Urban, a gynecologic oncologist at the University of Washington in Seattle. Neuropathy results from damage to the peripheral nerves. It usually resolves after chemotherapy treatment, but sometimes symptoms can persist. While it’s typically characterized by numbness or a pins-and-needles sensation in the hands and feet, neuropathy can have several different symptoms, including:
- Weakness in the hands or feet
- Stabbing or burning pain in the hands or feet
- Difficulty gripping, such as when holding a fork
- Difficulty with fine motor skills, such as writing or buttoning a shirt
Nausea and vomiting are common side effects of chemotherapy. When chemotherapy affects the rapidly dividing cells in the lining of the stomach, the resulting cellular havoc in the gastrointestinal tract can lead to side effects such as nausea and vomiting. However, doctors can help patients mitigate the hit with various medications before, during, and after treatment.
“Part of the chemotherapy prescription includes a set regimen of anti-nausea medications,” says Dr. Renata Urban, a gynecologic oncologist at the University of Washington in Seattle. “We also ensure that patients have medications at home that they can use should they develop nausea after treatment.”
Hair loss is another side effect of chemotherapy.
WATCH: Coping with hair loss.
“For cancer patients, losing one’s hair can be unbelievably stressful. To start with, the dread of losing one’s hair can lead to some sleepless nights and feelings of anxiety,” Dr. Samantha Boardman, a New York-based psychiatrist and author, told SurvivorNet.
Chemotherapy can cause hair loss. It usually begins about three to four weeks after chemotherapy and continues throughout treatment.
It happens because this treatment targets quickly dividing cells throughout the body. That includes cancer cells but also hair cells.
Most patients can expect regrowth four to six weeks after treatment. However, it is possible that when your hair grows back, you may notice some changes in its color and texture.
RELATED: How are chemotherapy side effects managed for ovarian cancer treatment?
Tips for Navigating Chemo Side Effects
When dealing with fatigue, doctors don’t have an arsenal of weapons to combat fatigue in terms of prescription medications. However, you can do several things to help minimize the hit and restore your energy.
- Exercise: While it may be counterintuitive, physical activity can help alleviate side effects, especially fatigue. “Although ovarian cancer is not common, we often draw upon the experience of patients with breast cancer and colon cancer, who have shown that physical activity can not only improve quality of life but may also have beneficial impacts on cancer outcomes,” Dr. Urban says.
- Eat well: Even though nausea may interfere with your ability to eat a healthy diet, it’s essential to ensure you’re eating appropriately, getting enough protein, and not losing weight. Not only will nourishing your body support your recovery, but it may also help you feel more energized.
- Sleep: Want to mitigate fatigue? Be sure to maintain your regular sleep-wake cycle while on treatment. Sticking to a set sleep schedule helps reduce fatigue by ensuring enough hours for your body to heal and restore itself each night. It may also help you recover more quickly by keeping energy levels high during the daytime.
Treating Neuropathy Symptoms
Doctors have several strategies for helping patients deal with this side effect. Once a patient begins experiencing the symptoms of neuropathy, they’ll be carefully monitored to make sure it doesn’t get worse. Before each chemotherapy infusion, the attending oncologist will assess whether the symptoms have progressed. If the symptoms worsen, they may adjust the dose or delay treatment. They may also try switching to another chemotherapy drug.
How to Get a Handle on Nausea
Most of these anti-nausea medications last for more than eight hours. One of the infusions commonly used reduces the degree of nausea for up to three days.
Complementary approaches may also be helpful. A few favorites:
- Ginger: Studies consistently show that ginger helps alleviate chemotherapy-induced nausea. The powerful herb appears to have an anti-spasmodic effect on the gut. Not a fan of raw ginger? Suck on ginger candy, sip ginger ale, or make a steaming cup of ginger tea.
- Pressure bracelets: at your local pharmacy, these bracelets provide consistent pressure on a particular acupressure point on the wrist to reduce nausea.
- Deep breathing: Moving air in and out of your lungs with a few deep breaths can help relieve nausea, particularly if you pair deep breathing exercises with meditation. It can also help you relax and release stress and anxiety.
WATCH: Managing chemo side effects.
Coping with Hair Loss
If losing your hair is a concern for you before cancer treatment, know you have options like wigs, hats, wraps, and scarves, among other things.
Another option that can minimize hair loss is cryotherapy, “just a fancy way for saying cold therapy,” says Dr. Renata Urban, gynecologic oncologist at the University of Washington in Seattle.
Cryotherapy involves wearing cold caps or special cooling caps before, during, and after each chemotherapy treatment.
Help Coping With a Breast Cancer Diagnosis
If you are facing a breast cancer diagnosis, your emotions are likely to run high, which is completely normal. Psychiatrist Dr. Lori Plutchik says emotions are often fluid when coping with a diagnosis.
“The patient or person going through the stressful event should accept that emotions will be fluid. You may feel fine one day and then feel a massive wave of stress the next. It’s also important for those you look to for support, whether that’s a therapist, friends, and family, or both, to understand the fluidity of stress-related emotions,” Dr. Plutchik said.
WATCH: How to cope with complex and changing emotions.
If a stressful event affects how you think and feel, it may be time to seek mental health treatment. This could mean traditional talk therapy, medication, changing lifestyle habits (like exercise and diet), seeking a support group, or many other approaches.
SurvivorNet experts suggest women needing a little extra help coping with a breast cancer diagnosis.
- Let your family and close friends know, and let them help. So many cancer survivors tell us they want and need support, but are often too preoccupied to make specific requests. Urge those close to you to jump in with whatever practical help they can offer.
- Keep a journal. It can be extremely cathartic to let those feelings loose on paper. Grab a pen and a nice journal and chronicle your thoughts throughout the day.
- Join a cancer support group. Groups in nearly every community offer opportunities to connect with others going through a similar journey. You’ll learn constructive insight from others who can tell you what to expect and how to stay strong on tough days.
- Consider seeing a therapist. Ask your doctor to refer you to a therapist so you can discuss your fears and concerns in a safe space. Often, vocalizing your thoughts and feelings rather than internalizing them can provide relief.
What To Ask Your Doctor
If you have been diagnosed with breast cancer, you may have questions about keeping your strength through treatment. Here are a few questions to help you begin the conversation with your doctor:
- What treatment will I be receiving?
- What side effects are associated with this treatment?
- Are there steps I can take daily to help minimize these side effects?
- What physical activity routine do you recommend for me during treatment?
- Do you have recommendations for someone who doesn’t particularly enjoy exercise?
- Can you recommend a dietician who can help me with healthy eating tips and weight maintenance?
- I’ve been having trouble sleeping. Do you have any treatment recommendations?
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