Breast Cancer Surgery Considerations
- “Bachelorette” star Katie Thurston, 34, shared that her tumor is continuing to shrink following her six-month scan, a hopeful sign in her stage 4 breast cancer treatment journey that her current treatment is working.
- Originally scheduled for a double mastectomy (removal of both breasts), Thurston has chosen to delay the procedure after consulting with her doctors, citing the need to stay on medication without interruption.
- While some patients believe a double mastectomy offers the best protection, experts emphasize that survival rates are similar between mastectomy and lumpectomy with radiation, depending on individual factors like tumor size, genetic mutations, and cancer location.
- A double mastectomy typically takes about two hours for tissue removal, but reconstruction—especially when using tissue from another part of the body—can extend surgery to 6–12 hours.
- Preventive mastectomies are an option for high-risk patients. Women with BRCA1 or BRCA2 mutations may consider risk-reducing mastectomies, though some opt for high-risk surveillance with regular imaging. As Dr. Elisa Port explains, “That’s not prevention, that’s early detection.”
“The tumor is still shrinking,” Thurston, 34, shared in a recent Instagram post, following her six-month check-in to assess whether her treatment is working.

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Her decision is one many breast cancer patients consider while weighing the timing and necessity of surgery, especially when treatment is showing signs of success.
Thurston first revealed her diagnosis in February 2025, announcing she had stage 3 triple-positive ductal carcinoma—a rare and aggressive subtype of luminal breast cancer. According to Cancer Cell International, “Triple-positive breast cancer (TPBC), a unique subtype of luminal breast cancer, is characterized by concurrent positivity for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2).”
This subtype accounts for only 5–10% of all breast cancer cases and typically requires a multi-pronged treatment approach, including chemotherapy, HER2-targeted therapy, and hormone (endocrine) therapy.

Thurston’s openness about her diagnosis and treatment decisions is helping to break down the complexities of breast cancer care, especially for younger women who are facing the disease. When it comes to her upcoming mastectomy, her decision to delay shines a light on some questions some breast cancer patients have before proceeding with the procedure.
Breast Cancer Surgery Decisions
When it comes to breast cancer surgery, there’s no one-size-fits-all approach. Choosing between a lumpectomy and a mastectomy is a deeply personal decision—one that depends on a range of medical and emotional factors.
“As a breast surgeon, my job is to help patients understand that their long-term survival with mastectomy is equivalent to that with lumpectomy and radiation,” says Dr. Sarah Cate, Chief of Breast Surgery at Stamford Hospital.
Still, many women request a double mastectomy (removal of both breasts), believing it offers the best protection against recurrence. But that’s not always the case. The size of the tumor, its genetic profile, and a patient’s family history all play a role in determining the most appropriate surgical path.
WATCH: Should I Have a Lumpectomy or Mastectomy?
“Mastectomy has very specific indications,” Dr. Cate explains.
“Some of the things that would predict a mastectomy are things like a large tumor size to breast ratio, or having cancer in more than one area of the breast, or having a genetic mutation.”
Katie Thurston, who recently shared her breast cancer journey publicly, is preparing for a double mastectomy. While this procedure is often part of treatment, it’s also used preventatively for women at high risk of developing breast cancer.
“A double mastectomy typically takes about two hours for the cancer part of the operation, the removal of the tissue,” says Dr. Elisa Port, Chief of Breast Surgery at Mount Sinai Health System.
“The real length, the total length of the surgery, can often depend on what type of reconstruction [a patient] has.”
WATCH: What Goes Into a Double Mastectomy
Today, most women choose to undergo some form of reconstruction, which can significantly extend the duration of surgery—especially when tissue is transferred from another part of the body.
“When you take tissue from another part of the body and transfer it to fill in the empty space where the breasts are, this is a very long operation,” Dr. Port says.
“It can take anywhere from six to 12 hours because it’s really like having a tummy tuck and then transferring the tissue and grafting the tissue, connecting the vessels, so those tissues have blood flow to live in,” Dr. Port adds.
For women with a strong family history or a known genetic mutation—such as BRCA1 or BRCA2—the decision to undergo a preventative mastectomy may be the most effective way to reduce their risk.
“Risk-reducing mastectomies are an operation where we take women at, usually, very high risk for getting breast cancer,” Dr. Port explains. “For genetic mutation carriers, who are the ones at the highest risk, there’s unfortunately only one way to actually prevent breast cancer.”
WATCH: Getting a Preventive Mastectomy
Women who test positive for a BRCA mutation typically face two options.
“One is what’s called high-risk surveillance, which means we check them every six months or so—mammograms, MRIs—with the hope that if, God forbid, they develop breast cancer, we pick it up early,” Dr. Port says. “But that’s not prevention, that’s early detection.”
“Early detection is a goal, it’s not a guarantee. For the woman who wants to be more proactive about actually preventing breast cancer, or as we say, reducing her risk, unfortunately, the only way to do that is to remove the actual tissue at risk, and that is the breast tissue,” she adds.
Expert Resources for Patients Considering a Mastectomy
- For Breast Reconstruction After Mastectomy, Women May Choose ‘Now,’ ‘Later,’ or ‘Never’
- Mastectomy Network Founder Calls Out Facebook for Sexist Image Policing
- Mastectomy Friendly Swimsuits Are Easier To Find: Fashion Stylist And Breast Cancer Survivor On What To Look For
- Is a Preventative Mastectomy Right for Me?
- Implant Reconstruction After a Mastectomy: The Options
- Should I Have a Lumpectomy or Mastectomy?
- The Last Frontier: The Promise of Restoring Sensation After Mastectomy
- To Reconstruct or Not: After Mastectomy, Two Women Take Very Different Paths
- What Happens During a Double Mastectomy?
- What is Nipple-Sparing Mastectomy?
Katie’s Ongoing Treatment
Thurston previously shared that her treatment regimen includes three key medications:
- Kisqali (ribociclib): Approved by the FDA in 2017, this targeted therapy is used in combination with endocrine therapy to treat HR+/HER2- breast cancer. It works by slowing the progression of cancer, offering a more tolerable alternative to traditional chemotherapy.
- Lupron (leuprolide): A hormone therapy injection that lowers estrogen levels in the body, helping to prevent the cancer from growing.
- Letrozole: An aromatase inhibitor that reduces the body’s estrogen production, commonly used in postmenopausal women with hormone-sensitive breast cancer.
Treatment Options for Advanced Breast Cancer
Metastatic breast cancer (also called stage 4) means cancer cells have spread from the breast to other parts of the body, which may include the bones, liver, lungs, brain, and beyond.
Breast cancer spreads through the bloodstream or lymphatic system. The blood carries cancer cells to different body parts, where they grow as new tumors.
As the cancer spreads to other body parts, patients may experience additional symptoms depending on where the cancer has spread. Examples include:
- Bones: Severe bone pain or fractures
- Lungs: Difficulty breathing, chest pain, new cough
- Liver: Yellowing of the skin (jaundice), abdominal pain, nausea, and/or vomiting
- Brain: Headaches, memory loss, changes in vision, seizures
WATCH: Treatment options for metastatic breast cancer.
Although stage 4 breast cancer is not curable, several treatment options exist that can extend the life of patients. Treatment options depend on the stage, type of primary breast cancer, and whether hormone receptors are positive.
Treatment can include a combination of:
- Chemotherapy: Oral or IV medications that are toxic to tumor cells
- Hormonal therapies: Drugs that lower estrogen levels or block estrogen receptors from allowing the cancer cells to grow
- Targeted therapies: Drugs that target your tumor’s specific gene mutations
- Immunotherapy: Medications that stimulate your immune system to recognize and attack cancer cells
- Radiation: The use of high-energy rays to kill tumor cells and shrink tumors
- Surgery: To remove a cancerous tumor or lymph nodes (uncommon with stage IV; more common in stages I, II, and III)
- Clinical trials: Studies of new medications, treatments, and other therapies offer hope for better outcomes.
Questions to Ask Your Doctor
If you’re facing the option of having a mastectomy, here are some questions to consider asking your doctor:
- What can I do to prepare for a double mastectomy?
- What happens before and after the procedure?
- For reconstruction, what are the benefits of using implants over my own tissue and vice versa?
- What should I know about implants?
- What will recovery look like after the procedure?
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